{"id":"W1992316647","doi":"10.1054/bjoc.2001.1844","title":"p53 missense but not truncation mutations are associated with low levels of p21CIP1/WAF1mRNA expression in primary human sarcomas","year":2001,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Cancer Institute","keywords":"Biology; Missense mutation; Cancer research; Exon; Nonsense mutation; Cyclin-dependent kinase; Gene; Mutation; Tumor suppressor gene; Genetics; Cell cycle; Carcinogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001415081,0.0003291314,0.0004386406,0.0007283203,0.000288539,0.0002520166,0.00009079737,0.0002839933,0.00215328],"category_scores_gemma":[0.0005201612,0.0003869746,0.0001842701,0.0003152893,0.0004215574,0.0001171948,0.0002774032,0.0002937059,0.0008487614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002405371,"about_ca_system_score_gemma":0.0001907817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008828389,"about_ca_topic_score_gemma":0.001280538,"domain_scores_codex":[0.9997382,0.00003486839,0.00003073036,0.00005486116,0.00008914362,0.00005220023],"domain_scores_gemma":[0.9994544,0.0001205367,0.0001289507,0.00007624031,0.00007610657,0.000143731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002459044,0.00003330081,0.004815925,0.00004544768,0.00001202291,0.0009645642,0.00004508437,0.00005968375,0.9925987,0.00004788595,0.00007930896,0.001052306],"study_design_scores_gemma":[0.0001131719,0.001885123,0.3371759,0.00002147287,0.0001038594,0.03306416,0.0002294826,0.0008410228,0.621733,0.0003370862,0.004471081,0.00002471371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974704,0.000918811,0.0005691819,0.00002946335,0.000008966809,0.00001700077,0.0002724531,0.00003423674,0.0006795396],"genre_scores_gemma":[0.9971997,0.0006294944,0.000392695,0.00002106874,0.000007749206,0.00002248534,0.0006005741,0.00001074153,0.001115586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00215328,"threshold_uncertainty_score":0.00720346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01972037152735722,"score_gpt":0.2786494499669078,"score_spread":0.2589290784395506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}