{"id":"W1992336935","doi":"10.1074/jbc.m703988200","title":"Identification of Human Kinases Involved in Hepatitis C Virus Replication by Small Interference RNA Library Screening","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Hepatitis C virus research","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Steacie Institute for Molecular Sciences","funders":"","keywords":"Kinase; Virology; Identification (biology); RNA interference; Replication (statistics); Biology; Hepatitis C virus; RNA; Interference (communication); Computational biology; Viral replication; Cell biology; Virus; Genetics; Gene; Computer science; Computer network","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003664566,0.0006923717,0.000693661,0.0007759258,0.0003030338,0.0004602227,0.0003284859,0.0002866835,0.001749096],"category_scores_gemma":[0.0004233206,0.0002585329,0.0003857259,0.0005849679,0.0002224081,0.0001293404,0.0002018786,0.0003874728,0.0006727586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004438747,"about_ca_system_score_gemma":0.0004251431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005538492,"about_ca_topic_score_gemma":0.001622137,"domain_scores_codex":[0.9997513,0.0000406695,0.00002732213,0.00004208059,0.00008809051,0.00005056625],"domain_scores_gemma":[0.9997827,0.0001048915,0.00003527458,0.00002119382,0.00002725096,0.00002861542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002780488,0.00006862108,0.0004205079,0.00006070228,0.00001557627,0.0001039112,0.00001470642,0.0002755579,0.9937593,0.0001335755,0.0001445053,0.004725107],"study_design_scores_gemma":[0.00009044053,0.0006204678,0.004912776,0.000009506235,0.0001039574,0.0005812824,0.0000292878,0.003461381,0.9838448,0.0001044351,0.006226418,0.00001535564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9549422,0.004904673,0.02892388,0.0003136849,0.00008796567,0.0008298512,0.004656887,0.0004701156,0.004870625],"genre_scores_gemma":[0.94539,0.005133519,0.03195646,0.0001740932,0.00005023945,0.0006795488,0.01079919,0.00009751077,0.005719483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001749096,"threshold_uncertainty_score":0.005851328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07986691840846215,"score_gpt":0.343244259295262,"score_spread":0.2633773408867998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}