{"id":"W1992398204","doi":"10.1038/mt.2008.98","title":"Central Delivery of Dicer-substrate siRNA: A Direct Application for Pain Research","year":2008,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Dicer; Substrate (aquarium); Small interfering RNA; Cell biology; Chemistry; Neuroscience; Biology; RNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004867112,0.0001215889,0.0001399523,0.00005768547,0.00009891525,0.000007898098,0.0002424335,0.0001094804,0.000006545272],"category_scores_gemma":[0.00003920951,0.0001158219,0.0001493691,0.0001185688,0.0001261188,0.000003530907,0.00003056063,0.00007301992,0.000004461856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001299372,"about_ca_system_score_gemma":0.0001050501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009457654,"about_ca_topic_score_gemma":0.00001357681,"domain_scores_codex":[0.9988064,0.000180995,0.0001920951,0.0003213739,0.0001814211,0.0003176706],"domain_scores_gemma":[0.9992095,0.00002980896,0.00006181545,0.0003679105,0.0002681547,0.0000627789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003622958,0.0001029152,0.0009508008,0.00001064373,0.00007765092,0.000004748024,0.0000767304,0.00008855726,0.982433,0.00005243633,0.001230901,0.01460937],"study_design_scores_gemma":[0.0006012387,0.0008065367,0.001701649,0.000008922344,0.000004215804,0.000004985633,0.0000353394,0.0002339395,0.9733145,0.0001799089,0.02297316,0.0001356027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9774584,0.002375158,0.01881163,0.00008433367,0.00004001014,0.0004591475,0.00002050457,0.000009465933,0.0007413035],"genre_scores_gemma":[0.9967448,0.001921664,0.0003875529,0.0002637387,0.0001013053,0.0001438513,0.000124296,0.00002490982,0.0002878995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02174225,"threshold_uncertainty_score":0.4723081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04500031268235093,"score_gpt":0.3099383786243258,"score_spread":0.2649380659419748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}