{"id":"W1992405877","doi":"10.1006/bbrc.2000.4142","title":"Intersubunit Crosslinking of the Heterotetrameric Proton-Translocating Pyridine Nucleotide Transhydrogenase of Escherichia coli Defines Intersubunit Contacts between Transmembrane Helices of the β Subunits","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council","keywords":"Tetramer; Transmembrane domain; Protein subunit; Chemistry; Transmembrane protein; Cysteine; Cyclic nucleotide-binding domain; Stereochemistry; Crystallography; Nucleotide; Biophysics; Biochemistry; Amino acid; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0004449224,0.0001710932,0.0003060554,0.00005393599,0.0002871055,0.00002311606,0.001661532,0.0001362718,0.000007426147],"category_scores_gemma":[0.000431276,0.0001097445,0.0002422806,0.0008858021,0.002968406,0.00001287685,0.0005761351,0.000536307,7.373325e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001275433,"about_ca_system_score_gemma":0.0001363233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003738265,"about_ca_topic_score_gemma":0.00005669274,"domain_scores_codex":[0.997937,0.0004977569,0.0004850102,0.0002630678,0.0004711937,0.0003459488],"domain_scores_gemma":[0.9976612,0.0004432825,0.0001585103,0.001196984,0.0004136809,0.0001263634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001869397,0.0003194117,0.0041647,0.0002428415,0.00009379961,2.191645e-7,0.0002061248,0.000002077611,0.9928028,0.0001030963,0.00001540656,0.001862567],"study_design_scores_gemma":[0.0004587156,0.0002862353,0.004564879,0.0003143544,0.0000348046,0.000001206942,0.0002682859,0.0002647535,0.9925407,0.0000775861,0.001074829,0.0001136469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964756,0.0008504638,0.00007015875,0.001577153,0.00001117618,0.0007005636,0.0001132918,0.000005852247,0.0001957531],"genre_scores_gemma":[0.998539,0.00105331,0.0001610287,0.00003205106,0.00004805776,0.00006659605,0.00004518995,0.00002081115,0.00003397188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002681301,"threshold_uncertainty_score":0.999745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07719450140293291,"score_gpt":0.3610364420788524,"score_spread":0.2838419406759195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}