{"id":"W1992406580","doi":"10.1371/journal.pgen.0020009","title":"Genetic Analysis of Completely Sequenced Disease-Associated MHC Haplotypes Identifies Shuffling of Segments in Recent Human History","year":2006,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; National Institutes of Health; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV; Wellcome Trust; U.S. Department of Health and Human Services","keywords":"Haplotype; Biology; Genetics; Major histocompatibility complex; Human leukocyte antigen; Single-nucleotide polymorphism; Allele; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001927423,0.0001087336,0.0001974987,0.0007211837,0.0002029434,0.0002244724,0.0001474813,0.0002133108,0.001409547],"category_scores_gemma":[0.0005204912,0.0001079195,0.0001779454,0.0008574144,0.0002055801,0.000114215,0.0003213419,0.0002535421,0.0002735792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008819336,"about_ca_system_score_gemma":0.0001123499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005177248,"about_ca_topic_score_gemma":0.001174854,"domain_scores_codex":[0.9998907,0.0000256979,0.000007106908,0.00004727037,0.00001579513,0.00001338861],"domain_scores_gemma":[0.9997122,0.00009834173,0.00008130042,0.00002609746,0.00002018079,0.0000619504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001453034,0.00007387422,0.3201277,0.0003353377,0.0003407601,0.001681297,0.001269129,0.0009296458,0.610539,0.001039302,0.0003987141,0.06181226],"study_design_scores_gemma":[0.00002750825,0.0002742177,0.9805652,0.00004241567,0.0001228581,0.002189185,0.0001911624,0.001061065,0.01084419,0.0006034269,0.004064203,0.00001452954],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966806,0.0006858948,0.001616066,0.00002504181,0.000006385031,0.000008362613,0.0005899594,0.00001267352,0.0003749914],"genre_scores_gemma":[0.9949768,0.0003968328,0.002566867,0.00003557381,0.00001225199,0.00001376731,0.001605577,0.00001570043,0.0003766106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001409547,"threshold_uncertainty_score":0.004715443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03492385028840463,"score_gpt":0.2366327872737948,"score_spread":0.2017089369853902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}