{"id":"W1992468993","doi":"10.1074/jbc.m202376200","title":"The Mechanism of Docosahexaenoic Acid-induced Phospholipase D Activation in Human Lymphocytes Involves Exclusion of the Enzyme from Lipid Rafts","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Lipid raft; Docosahexaenoic acid; Mechanism (biology); Enzyme; Chemistry; Phospholipase; Cell biology; Phospholipase C; Biochemistry; Phospholipase D; Fatty acid; Membrane; Biology; Polyunsaturated fatty acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002277368,0.0001523743,0.0002598405,0.00001507905,0.00008329164,0.00001019869,0.0004630144,0.000300392,0.00007871654],"category_scores_gemma":[0.0002363824,0.0000766704,0.0002114661,0.0001040103,0.0001241245,0.000006935204,0.000158477,0.0002148816,2.125626e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003499174,"about_ca_system_score_gemma":0.00004338729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001855974,"about_ca_topic_score_gemma":0.000003852534,"domain_scores_codex":[0.9988576,0.0000798912,0.0005395956,0.0001670822,0.0001955052,0.0001603854],"domain_scores_gemma":[0.998872,0.00005458131,0.0006079011,0.0002868689,0.000125773,0.00005287204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001081221,0.0001052009,0.001072897,0.00001451017,0.00002697245,0.000001388191,0.00006133344,0.000003032822,0.9976851,0.000008888297,0.00007744924,0.0008350575],"study_design_scores_gemma":[0.0008253211,0.0001437905,0.002189773,0.00006385325,0.00002175583,0.00001219882,0.00011291,0.00001051868,0.9960477,0.000177808,0.0003010617,0.00009334334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990269,0.000473929,0.0000157715,0.0001240233,0.0001292377,0.00008830037,0.00001032184,0.000002233507,0.0001292797],"genre_scores_gemma":[0.9991835,0.0002739959,0.00004886615,0.00006329202,0.0003561351,0.000003401274,0.00001121493,0.000007520152,0.00005201175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001637482,"threshold_uncertainty_score":0.3126528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02328105294112836,"score_gpt":0.245482440741861,"score_spread":0.2222013878007326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}