{"id":"W1992470300","doi":"10.1002/hep.22228","title":"Hepatocytes can induce death of contacted cells via perforin-dependent mechanism","year":2008,"lang":"en","type":"article","venue":"Hepatology","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; Canadian Liver Foundation","keywords":"Mechanism (biology); Perforin; Cell biology; Chemistry; Biology; Biochemistry; Cytotoxicity; Philosophy; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001585098,0.0001790068,0.0006473499,0.0001875471,0.0001176791,0.000002622483,0.0001586703,0.0002411725,0.0008297713],"category_scores_gemma":[0.00006126909,0.0001603601,0.0001130741,0.0001258774,0.0001483731,0.00004863256,0.00009376098,0.0003687494,0.0001387259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008111799,"about_ca_system_score_gemma":0.0005290274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001344162,"about_ca_topic_score_gemma":0.00006813632,"domain_scores_codex":[0.9984006,0.0001032412,0.0004578191,0.0002806889,0.0003222045,0.0004354613],"domain_scores_gemma":[0.9990281,0.00006592481,0.0001319694,0.0004202622,0.0002099119,0.0001438164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004046593,0.0003924822,0.6744145,0.0001645796,0.0001973813,0.001058215,0.0009752082,9.002296e-7,0.3142956,0.006304061,0.0004593674,0.001333083],"study_design_scores_gemma":[0.003839622,0.001229631,0.0494603,0.0000456669,0.00007325054,0.001616754,0.0002800747,0.001893022,0.9346244,0.0007577706,0.005862704,0.0003168021],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928591,0.0003700963,0.0002822804,0.0002962476,0.0001612292,0.000426034,0.000008177813,0.00006197871,0.005534888],"genre_scores_gemma":[0.9974435,0.0005377821,0.0001532699,0.0002824721,0.00003369088,0.00003800195,0.00002336125,0.00002949761,0.001458417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6249542,"threshold_uncertainty_score":0.9085414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0380063819855089,"score_gpt":0.2771695309629221,"score_spread":0.2391631489774132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}