{"id":"W1992476706","doi":"10.1371/journal.pbio.0040242","title":"Metazoan Scc4 Homologs Link Sister Chromatid Cohesion to Cell and Axon Migration Guidance","year":2006,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Biotechnology and Biological Sciences Research Council; National Institute of General Medical Sciences; Medical Research Council; Natural Sciences and Engineering Research Council of Canada; March of Dimes Foundation; National Institutes of Health; Darwin Trust of Edinburgh; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust","keywords":"Biology; Establishment of sister chromatid cohesion; Cohesin; Caenorhabditis elegans; Genetics; Chromosome segregation; Cell biology; Chromatid; Drosophila melanogaster; Saccharomyces cerevisiae; Genetic screen; Sister chromatids; Chromatin; Mutant; Gene; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002997376,0.0003345499,0.00008008067,0.0002475513,0.0002303057,0.000234508,0.00015536,0.0002312777,0.003669771],"category_scores_gemma":[0.00009893984,0.0001714697,0.0001260973,0.00009262564,0.000143516,0.0001380683,0.0003461397,0.0002677341,0.0008442758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00038305,"about_ca_system_score_gemma":0.0002865381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002834312,"about_ca_topic_score_gemma":0.007798458,"domain_scores_codex":[0.9999572,0.000002936756,0.00000168826,0.00001120072,0.00001643924,0.00001050054],"domain_scores_gemma":[0.9999449,0.000004050687,0.00001634382,0.000006718381,0.00001154422,0.00001643769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003948859,0.000005254937,0.0006489876,0.00003209494,0.000005191596,0.00007749518,0.0000123272,0.00009639005,0.9968341,0.0001442123,0.0001823757,0.001922032],"study_design_scores_gemma":[0.00002783616,0.0001084221,0.0577331,0.00002386461,0.00003347294,0.0004895292,0.00007863648,0.00284735,0.9212811,0.0002691624,0.01709683,0.00001073651],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866115,0.002859795,0.003047222,0.0001294402,0.00004968426,0.00001708164,0.000689777,0.000354681,0.006240826],"genre_scores_gemma":[0.9881308,0.0007259527,0.001308123,0.00003650481,0.000006952655,0.00001068189,0.0007165204,0.00002406462,0.009040346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003669771,"threshold_uncertainty_score":0.01227659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005995657846983074,"score_gpt":0.2055986000344418,"score_spread":0.1996029421874587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}