{"id":"W1992476706","doi":"10.1371/journal.pbio.0040242","title":"Metazoan Scc4 Homologs Link Sister Chromatid Cohesion to Cell and Axon Migration Guidance","year":2006,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Biotechnology and Biological Sciences Research Council; National Institute of General Medical Sciences; Medical Research Council; Natural Sciences and Engineering Research Council of Canada; March of Dimes Foundation; National Institutes of Health; Darwin Trust of Edinburgh; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust","keywords":"Biology; Establishment of sister chromatid cohesion; Cohesin; Caenorhabditis elegans; Genetics; Chromosome segregation; Cell biology; Chromatid; Drosophila melanogaster; Saccharomyces cerevisiae; Genetic screen; Sister chromatids; Chromatin; Mutant; Gene; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001089765,0.0001676006,0.0001838488,0.00004705114,0.00007709495,0.0000223088,0.0001451991,0.0002260503,0.00001155566],"category_scores_gemma":[0.00002752462,0.0001520506,0.00005039412,0.00005649649,0.00006862313,0.00000262109,0.0001326577,0.00005875507,0.00002694046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001497268,"about_ca_system_score_gemma":0.00002422096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007025632,"about_ca_topic_score_gemma":0.000274698,"domain_scores_codex":[0.9990006,0.00006456264,0.0002453989,0.0004060404,0.00004543563,0.0002379314],"domain_scores_gemma":[0.9994774,0.00001416653,0.0000938068,0.000293459,0.00006013576,0.00006099631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002096712,0.00005596256,0.008054991,0.00002380447,0.0000163958,0.000001195883,0.00001736968,0.00004439675,0.9898767,0.0001591113,0.00111935,0.0006097565],"study_design_scores_gemma":[0.0007226058,0.001112139,0.02274911,0.00002052716,0.00005828022,0.00002466004,0.00002439145,0.00171146,0.9112756,0.001067047,0.06072965,0.0005044898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949431,0.0009098109,0.001551012,0.0008363295,0.00009019132,0.000217693,0.00003658498,0.00001670405,0.001398573],"genre_scores_gemma":[0.9907914,0.0001359386,0.007254825,0.0005561729,0.0002541764,0.0000341509,0.000376525,0.00002023133,0.0005765606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07860106,"threshold_uncertainty_score":0.6200444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005995657846983074,"score_gpt":0.2055986000344418,"score_spread":0.1996029421874587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}