{"id":"W1992527377","doi":"10.1016/j.pharmthera.2004.10.005","title":"Emerging role of cyclic ADP-ribose (cADPR) in smooth muscle","year":2004,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; Heart and Stroke Foundation of British Columbia and Yukon; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Ryanodine receptor; Cyclic ADP-ribose; Second messenger system; Intracellular; Inositol; Cell biology; Inositol trisphosphate; Cyclic adenosine monophosphate; Inositol trisphosphate receptor; Receptor; Signal transduction; Biology; Chemistry; Biochemistry; CD38","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007958604,0.000960234,0.001407863,0.001171451,0.0003961552,0.001295055,0.001103713,0.001710179,0.003573552],"category_scores_gemma":[0.0005706988,0.0002697187,0.0003623466,0.001397513,0.0008289653,0.001542403,0.0005784302,0.001994918,0.002720875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006963156,"about_ca_system_score_gemma":0.0009513113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008168311,"about_ca_topic_score_gemma":0.002207505,"domain_scores_codex":[0.9998653,0.00001975225,0.00001601871,0.0000293546,0.0000536741,0.000015965],"domain_scores_gemma":[0.9997802,0.000102234,0.00002468326,0.000009642912,0.00005583975,0.00002736893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0002168337,0.000120925,0.0001964752,0.004725919,0.00006397659,0.0007402432,0.00005377703,0.0004463189,0.01016651,0.005237717,0.02885669,0.9491746],"study_design_scores_gemma":[0.00006866226,0.0002657044,0.0006848187,0.0006836614,0.000122985,0.002086174,0.0000725656,0.0002002842,0.002533079,0.002822531,0.9904384,0.00002114758],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003833571,0.9953269,0.0007366693,0.0008396936,0.0007059071,0.00000751096,0.00001595312,0.00001999754,0.001964118],"genre_scores_gemma":[0.001695588,0.993856,0.0008957857,0.0006394149,0.0007475614,0.00001403807,0.00003302511,0.000002894061,0.002115713],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003573552,"threshold_uncertainty_score":0.01195478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03067189346650085,"score_gpt":0.3590100019686581,"score_spread":0.3283381085021572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}