{"id":"W1992552864","doi":"10.1371/journal.pone.0077204","title":"NADPH Oxidase Deficient Mice Develop Colitis and Bacteremia upon Infection with Normally Avirulent, TTSS-1- and TTSS-2-Deficient Salmonella Typhimurium","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Biology; Microbiology; Chronic granulomatous disease; NADPH oxidase; Immunology; Enteropathy; Lamina propria; Intestinal mucosa; Proinflammatory cytokine; Immune system; Inflammation; Medicine; Reactive oxygen species; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002446418,0.00121384,0.0004952326,0.0008510391,0.0002877413,0.0005099567,0.0004517923,0.001195698,0.003145359],"category_scores_gemma":[0.0002150741,0.0006825081,0.0005706465,0.0002828359,0.000670446,0.0004324391,0.0004364459,0.001566629,0.001020199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003891586,"about_ca_system_score_gemma":0.0002469867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007138134,"about_ca_topic_score_gemma":0.00113597,"domain_scores_codex":[0.9996021,0.00004261207,0.00005094631,0.0001277893,0.00007329918,0.000103173],"domain_scores_gemma":[0.9992318,0.00006188668,0.0002885433,0.0000631766,0.00003460333,0.0003201062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004834089,0.0001441271,0.0004738666,0.00004416697,0.00001199758,0.0002506112,0.00004429769,0.00007205766,0.9974619,0.0001352903,0.00007538641,0.0008028497],"study_design_scores_gemma":[0.0002525608,0.003548323,0.03666977,0.00008099025,0.00008403177,0.004205134,0.0002351121,0.002290471,0.9481462,0.0004209771,0.004021712,0.0000447031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917721,0.0007339491,0.003446968,0.000234966,0.00006140729,0.00006532147,0.001699283,0.0005022719,0.001483793],"genre_scores_gemma":[0.9795197,0.0007830385,0.004590865,0.0001929098,0.00003157274,0.0001564489,0.002056749,0.0001814977,0.01248721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003145359,"threshold_uncertainty_score":0.01052231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0197149222461967,"score_gpt":0.1903548622005485,"score_spread":0.1706399399543518,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}