{"id":"W1992558089","doi":"10.1073/pnas.181348298","title":"Phospholamban domain IB forms an interaction site with the loop between transmembrane helices M6 and M7 of sarco(endo)plasmic reticulum Ca <sup>2+</sup> ATPases","year":2001,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Medical Research Council; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Phospholamban; Mutant; Transmembrane domain; SERCA; Mutagenesis; Biology; Endoplasmic reticulum; Wild type; Chimera (genetics); Chemistry; Cell biology; ATPase; Genetics; Biochemistry; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005396181,0.0001007715,0.0001258695,0.0000635027,0.0001591274,0.00001765422,0.0002935981,0.00008567303,0.00000620542],"category_scores_gemma":[0.00002219398,0.00005526413,0.00005183133,0.0002740216,0.0006304701,0.00007534998,0.00002471622,0.00008775979,1.629511e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007174402,"about_ca_system_score_gemma":0.00002112974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002299316,"about_ca_topic_score_gemma":0.000002665224,"domain_scores_codex":[0.9989374,0.000007071752,0.0002331225,0.000215224,0.0004865275,0.0001206733],"domain_scores_gemma":[0.9994735,0.00002354687,0.0002792629,0.00001460186,0.0001783628,0.00003068873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002461695,0.00005649962,0.03815045,0.00009771648,0.00004530696,1.817281e-8,0.001129855,0.001049551,0.9574153,0.001020763,0.00007287312,0.0007154472],"study_design_scores_gemma":[0.0003923135,0.0003300835,0.06016334,0.00008180786,0.00003579536,0.00001927713,0.001660146,0.0009271037,0.9342552,0.001409886,0.000621449,0.0001036191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976783,0.0001305882,0.00001319635,0.00161968,0.00000540167,0.00015789,0.00002452946,0.000003574359,0.0003668184],"genre_scores_gemma":[0.9994255,0.0001158028,0.0002032264,0.00008602384,0.00007904546,0.000006517621,0.000007018024,0.000005001169,0.00007181577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02316017,"threshold_uncertainty_score":0.2322993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01674110636376946,"score_gpt":0.2634242773499521,"score_spread":0.2466831709861826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}