{"id":"W1992564715","doi":"10.2337/dc13-0425","title":"The Prediction of Type 1 Diabetes by Multiple Autoantibody Levels and Their Incorporation Into an Autoantibody Risk Score in Relatives of Type 1 Diabetic Patients","year":2013,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; U.S. National Library of Medicine; National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Center for Research Resources; American Diabetes Association","keywords":"Autoantibody; Medicine; Type 1 diabetes; Internal medicine; Diabetes mellitus; Receiver operating characteristic; Type 2 diabetes; Endocrinology; Gastroenterology; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003179931,0.0006161495,0.0005413915,0.000620315,0.0002383953,0.0005130399,0.0002953387,0.000427812,0.0007966939],"category_scores_gemma":[0.008085779,0.0002313937,0.0005333915,0.0005606757,0.000183076,0.0004372452,0.0004172649,0.0006082208,0.000185183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001945623,"about_ca_system_score_gemma":0.0002337388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001262127,"about_ca_topic_score_gemma":0.001598699,"domain_scores_codex":[0.9988097,0.0007583285,0.00006259505,0.0001550026,0.0001614211,0.00005290329],"domain_scores_gemma":[0.9965801,0.001698291,0.0009973219,0.0002337361,0.0001890882,0.0003013842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001280095,0.00005347078,0.9922531,0.00001607663,0.0001690474,0.000130877,0.00005192584,0.0006406473,0.0002945042,0.00001953023,0.00007573092,0.005014979],"study_design_scores_gemma":[0.0001566903,0.001612312,0.9782885,0.00004693315,0.0006494678,0.001252558,0.0001974407,0.01626387,0.0006140376,0.0004376326,0.0004493454,0.00003111519],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987906,0.0004161734,0.0004254371,0.00006212688,0.00001523599,0.000004106213,0.00005186343,0.000007768464,0.0002267143],"genre_scores_gemma":[0.9993398,0.00007214108,0.0004366626,0.000009677395,0.00001851509,0.000002787462,0.00004703245,0.000001419913,0.00007211935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003179931,"threshold_uncertainty_score":0.01681733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005844806115835899,"score_gpt":0.20848144770709,"score_spread":0.2026366415912541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}