{"id":"W1992579096","doi":"10.1089/104454903321515887","title":"Differential DNA Binding of Ku Antigen Determines Its Involvement in DNA Replication","year":2003,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Biology; Origin recognition complex; Eukaryotic DNA replication; Replication factor C; DNA replication; Ku70; Control of chromosome duplication; Ku80; DNA replication factor CDT1; Replication protein A; Molecular biology; DNA polymerase II; Origin of replication; Pre-replication complex; DNA; DNA-binding protein; Gene; DNA repair; Genetics; Transcription factor; Reverse transcriptase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002255649,0.0002394932,0.0002178186,0.0003159459,0.000203675,0.000377772,0.0002428146,0.0003533156,0.0009241355],"category_scores_gemma":[0.000349961,0.0001915801,0.0003564247,0.0001080391,0.0003080595,0.0003289635,0.000309791,0.0004621199,0.0004552805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002722753,"about_ca_system_score_gemma":0.0001550328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003578364,"about_ca_topic_score_gemma":0.0003116442,"domain_scores_codex":[0.9995545,0.00006901316,0.00002656019,0.000118472,0.00009977856,0.0001317632],"domain_scores_gemma":[0.9994947,0.0001481649,0.0001189453,0.00004884624,0.0000560734,0.0001332479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003981089,0.000006191814,0.0004332972,0.000008019699,0.000002121692,0.00001577844,0.000009804981,0.00001366211,0.9990788,0.0000479311,0.000002278991,0.0003423236],"study_design_scores_gemma":[0.000004438368,0.0002089275,0.02575078,0.000004637246,0.00001702226,0.0003592361,0.00006067071,0.0007612117,0.9719928,0.0001045249,0.0007283079,0.000007383364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974981,0.0006044603,0.001261951,0.0000127857,0.000004345542,0.000004013875,0.00002356933,0.00001897955,0.0005716732],"genre_scores_gemma":[0.9984084,0.0001582607,0.0008380483,0.0000110131,0.000003024824,0.000004516772,0.00007572374,0.000008005448,0.0004932226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009241355,"threshold_uncertainty_score":0.003091574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01316098638244305,"score_gpt":0.2420251183269858,"score_spread":0.2288641319445427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}