{"id":"W1992584891","doi":"10.2147/ijn.s47413","title":"Linear polyethylenimine produced by partial acid hydrolysis of poly(2-ethyl-2-oxazoline) for DNA and siRNA delivery in vitro","year":2013,"lang":"en","type":"article","venue":"International Journal of Nanomedicine","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Canadian Institutes of Health Research; Science and Technology Commission of Shanghai Municipality","keywords":"Polyethylenimine; Small interfering RNA; Transfection; Gene delivery; Gene knockdown; RNA; DNA; Gene silencing; Chemistry; Molecular biology; Biophysics; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002508979,0.0001294073,0.000269305,0.0001910139,0.0000139032,0.00001077462,0.0002728713,0.00009094494,0.00003332621],"category_scores_gemma":[0.0002060402,0.0001051137,0.0001065993,0.00005925833,0.00008566331,0.00002117561,0.00006134392,0.00009856014,0.000001604907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002033994,"about_ca_system_score_gemma":0.00007329034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000657983,"about_ca_topic_score_gemma":0.00000491864,"domain_scores_codex":[0.9988065,0.00002759596,0.000587458,0.0001758189,0.0002496523,0.0001529329],"domain_scores_gemma":[0.9988471,0.00003286216,0.0003493447,0.0001125422,0.0005730234,0.00008513196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009258331,0.00009347069,0.001159157,0.00001066913,0.0001796015,0.000005771366,0.00006852538,0.000005878007,0.9820064,0.000001835878,0.001715508,0.01382736],"study_design_scores_gemma":[0.002063425,0.0008376812,0.001060574,0.00005789518,0.00003293595,0.00004961599,0.00007617986,0.0003263438,0.9926153,0.00003511565,0.00274726,0.00009765485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919871,0.004022301,0.0007932376,0.002605043,0.0003947396,0.000133697,0.00004305599,0.000001624589,0.00001917441],"genre_scores_gemma":[0.9970368,0.000815566,0.0005636238,0.0004330312,0.0009179011,0.000009851376,0.00006410573,0.0000126712,0.0001464614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01372971,"threshold_uncertainty_score":0.4286412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008204733332418588,"score_gpt":0.2534073819959233,"score_spread":0.2452026486635047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}