{"id":"W1992584891","doi":"10.2147/ijn.s47413","title":"Linear polyethylenimine produced by partial acid hydrolysis of poly(2-ethyl-2-oxazoline) for DNA and siRNA delivery in vitro","year":2013,"lang":"en","type":"article","venue":"International Journal of Nanomedicine","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Canadian Institutes of Health Research; Science and Technology Commission of Shanghai Municipality","keywords":"Polyethylenimine; Small interfering RNA; Transfection; Gene delivery; Gene knockdown; RNA; DNA; Gene silencing; Chemistry; Molecular biology; Biophysics; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003841294,0.0004897794,0.0002437782,0.0002118643,0.0001055311,0.0001887276,0.0001880242,0.0002890754,0.001706982],"category_scores_gemma":[0.000236786,0.00023005,0.0003011821,0.0002113136,0.0001523782,0.0002637264,0.0001731907,0.0004628627,0.0006941917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001879291,"about_ca_system_score_gemma":0.0002603209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003131981,"about_ca_topic_score_gemma":0.0005770381,"domain_scores_codex":[0.9998271,0.00003623427,0.00002451467,0.00003673972,0.00004255481,0.00003290756],"domain_scores_gemma":[0.9999022,0.00003219105,0.00002521782,0.00001165639,0.00001573798,0.0000128784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001914635,0.0000074289,0.00001658493,0.0000397265,0.000001719216,0.00002120197,0.000007271718,0.00004531015,0.9987546,0.00003989084,0.00001176636,0.001035372],"study_design_scores_gemma":[0.00000711225,0.0001085697,0.0001954978,0.000002985642,0.00000532295,0.00005216573,0.00000246844,0.0003245635,0.9974734,0.00001708909,0.001807913,0.000002797405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8709952,0.006190533,0.1153766,0.0001469829,0.0001405345,0.0005767721,0.000632303,0.000552187,0.005388966],"genre_scores_gemma":[0.9114218,0.003257694,0.07205035,0.0001292828,0.00002689018,0.0005716309,0.001610794,0.0001095775,0.01082196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001706982,"threshold_uncertainty_score":0.005710423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008204733332418588,"score_gpt":0.2534073819959233,"score_spread":0.2452026486635047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}