{"id":"W1992593101","doi":"10.1371/journal.ppat.1002916","title":"Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism","year":2012,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Basic Energy Sciences; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Canadian Institutes of Health Research; U.S. Public Health Service; Office of Science; National Institutes of Health; Thailand Science Research and Innovation; Burroughs Wellcome Fund; U.S. Department of Energy","keywords":"Marburg virus; Ebolavirus; Virology; RNA silencing; Biology; Ebola virus; VP40; Interferon; RNA; Virus; RNA interference; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007743384,0.000279571,0.0002002272,0.000100999,0.0002080185,0.0003665235,0.0002236894,0.0002831611,0.0007697824],"category_scores_gemma":[0.000172872,0.0001933403,0.0002799541,0.00005959698,0.0001971401,0.000332576,0.0002979644,0.0006386449,0.0003636564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003640677,"about_ca_system_score_gemma":0.0001687536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004526247,"about_ca_topic_score_gemma":0.0008227623,"domain_scores_codex":[0.9999199,0.000009292261,0.000003203672,0.0000200381,0.00002974828,0.00001776409],"domain_scores_gemma":[0.9999362,0.00001129028,0.00001706143,0.00001019482,0.000008296843,0.00001684164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004160608,0.00001846426,0.0005676498,0.00002556613,0.000008359155,0.00007826588,0.00002652499,0.0002214115,0.995858,0.0005144581,0.00008044116,0.002559319],"study_design_scores_gemma":[0.00001859383,0.0001552177,0.004007974,0.000009232165,0.00001554503,0.0003564456,0.00003609296,0.004353852,0.9816598,0.0003192983,0.00905505,0.00001292803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873065,0.001331277,0.008104763,0.00008620674,0.0000341796,0.00002226749,0.0001243239,0.0001796149,0.002810886],"genre_scores_gemma":[0.9910021,0.0003808484,0.006130747,0.00004900485,0.00001310756,0.00001737511,0.0003399866,0.00001811988,0.002048759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007697824,"threshold_uncertainty_score":0.002641499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04902036364467667,"score_gpt":0.3082256736579798,"score_spread":0.2592053100133031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}