{"id":"W1992617948","doi":"10.1128/aac.50.1.88-95.2006","title":"Resistance of<i>Leishmania donovani</i>to Sodium Stibogluconate Is Related to the Expression of Host and Parasite γ-Glutamylcysteine Synthetase","year":2005,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Royal Society","keywords":"Leishmania donovani; Sodium stibogluconate; Parasite hosting; Host (biology); Biology; Leishmania; Molecular biology; Virology; Protozoal disease; Genetics; Leishmaniasis; Immunology; Malaria; Visceral leishmaniasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002842354,0.0002160644,0.0004818265,0.0001168012,0.0001357019,0.00002458355,0.0001560317,0.00007641132,0.0001083424],"category_scores_gemma":[0.00004612896,0.0001454927,0.00007476466,0.0002709369,0.0001787818,0.0000797239,0.000119243,0.0001359387,0.00001281043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002299901,"about_ca_system_score_gemma":0.00002762168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005783017,"about_ca_topic_score_gemma":0.00004456458,"domain_scores_codex":[0.9985775,0.00004496635,0.0004271175,0.0003792608,0.0002708069,0.0003003622],"domain_scores_gemma":[0.9990942,0.0000608048,0.0001367778,0.00038722,0.0001645092,0.0001564191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001754806,0.0002751889,0.01594366,0.0002404337,0.0002213183,0.00001415766,0.00431274,0.000004221974,0.8534182,0.0000362778,0.1166694,0.007109649],"study_design_scores_gemma":[0.002779912,0.000295563,0.09013525,0.0007042921,0.00005456807,0.00002255629,0.0001389131,0.00002023944,0.6958157,0.0000117499,0.2098105,0.0002107487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9560966,0.0004371777,0.00003495695,0.0421494,0.00003989402,0.0007266099,0.00008066599,0.00001867386,0.0004159974],"genre_scores_gemma":[0.9836379,0.003063701,0.001432484,0.00913193,0.00006002386,0.00001021521,0.000005755613,0.00003329322,0.002624752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1576025,"threshold_uncertainty_score":0.5933018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01256492803473515,"score_gpt":0.2836685975088726,"score_spread":0.2711036694741374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}