{"id":"W1992667040","doi":"10.1016/j.jmb.2004.12.009","title":"Tn10 Transposase Mutants with Altered Transpososome Unfolding Properties are Defective in Hairpin Formation","year":2004,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Tn10; Transposase; Transposable element; Mutant; Transposition (logic); DNA; Context (archaeology); Biology; Genetics; Cell biology; Gene; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002079878,0.0008566635,0.0003953746,0.000383044,0.000221646,0.0004647709,0.000592575,0.000738278,0.002418943],"category_scores_gemma":[0.0003388896,0.000371068,0.0004746443,0.0002669453,0.0005505754,0.0002659175,0.000445939,0.001056042,0.0009429653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004197175,"about_ca_system_score_gemma":0.0002930368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001665687,"about_ca_topic_score_gemma":0.001912839,"domain_scores_codex":[0.9997705,0.00004216806,0.000026688,0.00003528256,0.00007705743,0.00004825416],"domain_scores_gemma":[0.9994129,0.0001593631,0.00016658,0.00006129841,0.00004353546,0.0001564508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004735309,0.00002097178,0.00005611393,0.000008466484,0.000004206663,0.00006536015,0.000009756766,0.00004629123,0.999338,0.00008044805,0.00001521996,0.0003078297],"study_design_scores_gemma":[0.00001285198,0.0001064517,0.002320755,0.00000362158,0.00001451954,0.0004366937,0.00003668405,0.00108272,0.9953603,0.00005864604,0.000555338,0.00001151887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938741,0.0001887796,0.004486338,0.00006822684,0.0000504669,0.00003092978,0.0003294045,0.0002160535,0.0007556161],"genre_scores_gemma":[0.9950951,0.00009190985,0.001879959,0.00003728262,0.000008385451,0.00002671665,0.0005030849,0.0001365124,0.002221043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002418943,"threshold_uncertainty_score":0.008092165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009753136161078129,"score_gpt":0.2530596603477545,"score_spread":0.2433065241866763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}