{"id":"W1992714085","doi":"10.1038/oby.2005.52","title":"Leptin Receptor Gene Variation Predicts Weight Change in Subjects with Impaired Glucose Tolerance","year":2005,"lang":"en","type":"article","venue":"Obesity Research","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Internal medicine; Endocrinology; Impaired glucose tolerance; Type 2 diabetes; Leptin; Medicine; Diabetes mellitus; Obesity; Allele; Leptin receptor; Polymorphism (computer science); Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00132799,0.0001609257,0.000201395,0.0003263374,0.0003258487,0.0001109212,0.0004119037,0.0001308916,0.0004016372],"category_scores_gemma":[0.0002976225,0.0001427374,0.00003796587,0.0012591,0.000169804,0.0007113371,0.0001368002,0.0004370214,0.0006621744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000249471,"about_ca_system_score_gemma":0.0001320945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003036663,"about_ca_topic_score_gemma":0.0007125899,"domain_scores_codex":[0.9967841,0.0005697852,0.0002385262,0.0006424456,0.001085296,0.0006798537],"domain_scores_gemma":[0.9988623,0.0002531326,0.00006884515,0.0004626634,0.0001637249,0.0001893406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008759605,0.00137512,0.1522933,0.00008811378,0.000006217118,0.00007581257,0.004090895,0.000356229,0.8235633,0.002090903,0.001174684,0.01400948],"study_design_scores_gemma":[0.0009074405,0.0002062541,0.4518886,0.00006222229,0.000001537592,0.000007429225,0.00001056776,0.005772278,0.5361356,0.000103985,0.004751498,0.0001526163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948505,0.0001007656,0.0000777648,0.002171028,0.00007509256,0.0007997411,0.00001323421,0.00008853273,0.001823351],"genre_scores_gemma":[0.9966953,0.0003077355,0.0007833912,0.000233848,0.0005547298,0.00008783861,0.00001047042,0.00002322893,0.001303419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2995953,"threshold_uncertainty_score":0.8511134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06666975045936897,"score_gpt":0.3200471708164179,"score_spread":0.2533774203570489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}