{"id":"W1992739435","doi":"10.1159/000094084","title":"Tracing the Evolution and Function of the Trk Superfamily of Receptor Tyrosine Kinases","year":2006,"lang":"en","type":"review","venue":"Brain Behavior and Evolution","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Trk receptor; Receptor tyrosine kinase; Biology; Tropomyosin receptor kinase C; Receptor Protein-Tyrosine Kinases; ROR1; Receptor; Cell biology; Tyrosine kinase; Functional divergence; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Platelet-derived growth factor receptor; Biochemistry; Neurotrophin; Gene; Gene family; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005286754,0.0007957538,0.0009181888,0.00207607,0.0002917439,0.0008758365,0.0009829524,0.0009552863,0.002211733],"category_scores_gemma":[0.0005655346,0.000289004,0.0001998459,0.002414976,0.000714205,0.001648113,0.0005284837,0.0012721,0.003119218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001028855,"about_ca_system_score_gemma":0.0008914061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001639726,"about_ca_topic_score_gemma":0.001943827,"domain_scores_codex":[0.9998479,0.00002066942,0.00001484829,0.00003581048,0.00006940607,0.00001133012],"domain_scores_gemma":[0.9997864,0.00006315744,0.00003190612,0.00001050897,0.00007866691,0.00002925024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007370768,0.00003968718,0.0002847925,0.006074914,0.00004474508,0.0003616849,0.00009611927,0.000647773,0.004356227,0.008993629,0.01991414,0.9591125],"study_design_scores_gemma":[0.000009323841,0.00004016926,0.0009872883,0.000900317,0.00003219185,0.001093834,0.0000536329,0.00009815034,0.001006977,0.002829359,0.9929369,0.0000117966],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002877741,0.9969538,0.0004068789,0.0002786987,0.0001543469,0.000003135805,0.00001415141,0.000009728097,0.001891521],"genre_scores_gemma":[0.001263508,0.996444,0.0005355361,0.0001100744,0.0001435522,0.000003952887,0.00002562625,0.000002247498,0.001471388],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002211733,"threshold_uncertainty_score":0.007464886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01894054576994953,"score_gpt":0.2619453851246885,"score_spread":0.2430048393547389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}