{"id":"W1992751927","doi":"10.1086/505882","title":"Characterization of Human Cytomegalovirus (HCMV) UL97 Mutations Found in a Valganciclovir/Oral Ganciclovir Prophylactic Trial by Use of a Bacterial Artificial Chromosome Containing the HCMV Genome","year":2006,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Valganciclovir; Ganciclovir; Human cytomegalovirus; Virology; Biology; Recombinant DNA; Bacterial artificial chromosome; Cytomegalovirus; Mutation; Genome; Herpesviridae; Virus; Gene; Genetics; Viral disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006677817,0.0003409856,0.0006441001,0.0003038374,0.0001489685,0.0004175548,0.0002311972,0.0005120023,0.0008484885],"category_scores_gemma":[0.0009258321,0.0001508922,0.0002746188,0.0002874739,0.0003355393,0.0001830083,0.0001215803,0.0007043502,0.0001205806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00032076,"about_ca_system_score_gemma":0.0003458356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004834067,"about_ca_topic_score_gemma":0.0005210037,"domain_scores_codex":[0.9996157,0.00008710058,0.00004937679,0.00005859592,0.0001107855,0.0000784896],"domain_scores_gemma":[0.9997126,0.0001307218,0.00005396115,0.00002512116,0.00002581776,0.00005164692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01327157,0.0024204,0.01489427,0.0001352474,0.000136982,0.001293773,0.0002291874,0.001084883,0.929774,0.0004052191,0.0002402926,0.03611412],"study_design_scores_gemma":[0.004633418,0.07620086,0.05009391,0.00002272514,0.0003242434,0.004112737,0.00009666085,0.003207837,0.8554128,0.0001645248,0.005699832,0.00003030959],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976876,0.0006449569,0.000651181,0.00004957541,0.00002149886,0.0002028322,0.0001776102,0.00001097278,0.000553744],"genre_scores_gemma":[0.9976667,0.0003030844,0.00107326,0.00005234919,0.0000138272,0.0001056625,0.000310142,0.00001049255,0.000464526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008484885,"threshold_uncertainty_score":0.003531575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03207737897056872,"score_gpt":0.3030477387209184,"score_spread":0.2709703597503497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}