{"id":"W1992816755","doi":"10.1016/j.ica.2012.06.039","title":"Synthesis and in vitro anticancer activity of ferrocenyl-aminoquinoline-carboxamide conjugates","year":2012,"lang":"en","type":"article","venue":"Inorganica Chimica Acta","topic":"Ferrocene Chemistry and Applications","field":"Chemistry","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Killam Trusts; Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología","keywords":"Chemistry; In vitro; Cytotoxicity; Amide; Carboxamide; Human breast; Conjugate; Ferrocene; Cell culture; Pharmacology; Caco-2; Combinatorial chemistry; Biochemistry; Cancer research; Stereochemistry; Cancer cell; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001216592,0.000223835,0.0003655085,0.00004035442,0.00006837929,0.0000155191,0.0002777194,0.0001915258,0.0003405868],"category_scores_gemma":[0.0003161171,0.0002266798,0.00005694346,0.0001880884,0.000184974,0.000183221,0.000149713,0.0003278467,0.000007425271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006473073,"about_ca_system_score_gemma":0.0000556917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003282446,"about_ca_topic_score_gemma":0.000006262843,"domain_scores_codex":[0.9987992,0.00001983585,0.0003124611,0.0003092413,0.0001524002,0.0004068503],"domain_scores_gemma":[0.9987687,0.0004049053,0.000163709,0.0004623349,0.00003879685,0.0001615243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001051898,0.0002927936,0.00938191,0.0001868466,0.00002969776,2.741662e-7,0.0001664286,1.696304e-7,0.989569,0.00002154483,0.00005775836,0.0001884038],"study_design_scores_gemma":[0.0002718389,0.000002763625,0.0173512,0.0000564027,0.00004786694,0.00001437578,0.0000922003,0.00007960457,0.981374,0.00003912733,0.0004403063,0.0002303749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994076,0.0001236082,0.000001685225,0.0005504216,0.00002147593,0.00006139663,0.0000867186,0.00005800841,0.005020671],"genre_scores_gemma":[0.9992979,0.0001804276,0.0001797734,0.00004854422,0.0001384839,0.00003741245,0.00001196949,0.00003294913,0.00007250433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008195042,"threshold_uncertainty_score":0.9243736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01529974331666937,"score_gpt":0.2427045513796449,"score_spread":0.2274048080629756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}