{"id":"W1992843439","doi":"10.1186/1472-6750-12-87","title":"A novel strategy for efficient production of anti-V3 human scFvs against HIV-1 clade C","year":2012,"lang":"en","type":"article","venue":"BMC Biotechnology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Brain Research Centre; Department of Biotechnology, Ministry of Science and Technology, India; York University","keywords":"Biology; Phagemid; Virology; Phage display; Antibody; Peptide library; Panning (audio); Monoclonal antibody; Neutralization; Molecular biology; Antigen; Cloning (programming); Recombinant DNA; Transformation (genetics); Gene; Virus; Genetics; Bacteriophage; Peptide sequence; Escherichia coli","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002361856,0.0005923937,0.0003305622,0.0003297856,0.0002046173,0.0004491245,0.0004420446,0.000586955,0.0008524196],"category_scores_gemma":[0.0001240729,0.0001843666,0.0004225645,0.0003317306,0.0001545672,0.000285971,0.0004684031,0.0007585269,0.0005657006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003083789,"about_ca_system_score_gemma":0.00023955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003290197,"about_ca_topic_score_gemma":0.0004093276,"domain_scores_codex":[0.9997932,0.00002918136,0.00001617996,0.00004086974,0.00007530642,0.00004515049],"domain_scores_gemma":[0.9999436,0.00000695448,0.00001555382,0.000008474516,0.00001185824,0.00001368197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003405174,0.00004462553,0.0001138621,0.00006688681,0.00001173944,0.0001144528,0.00001791579,0.0001723618,0.9924961,0.0002384385,0.000228279,0.006461239],"study_design_scores_gemma":[0.0000360614,0.0003746508,0.001255283,0.0000183539,0.00003685212,0.001116884,0.00002257892,0.003522686,0.9776738,0.0001637195,0.01576176,0.00001746801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7533566,0.005240801,0.2318458,0.000463755,0.0002439623,0.0006415251,0.001202802,0.0005291678,0.006475443],"genre_scores_gemma":[0.8667256,0.00386949,0.1206583,0.0004137564,0.00004385591,0.0003492604,0.0022798,0.00008097953,0.005579026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008524196,"threshold_uncertainty_score":0.002851605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0779758015630838,"score_gpt":0.3520646321073237,"score_spread":0.2740888305442399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}