{"id":"W1992888087","doi":"10.1038/35001095","title":"Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands","year":2000,"lang":"en","type":"article","venue":"Nature","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":864,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Shiga toxin; Oligosaccharide; Toxin; Protein subunit; Chemistry; Shiga-like toxin; Biochemistry; Escherichia coli; Cholera toxin; Receptor; Ligand (biochemistry); Trisaccharide; Carbohydrate; Biology; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001330613,0.0003730203,0.0001869051,0.0001316688,0.000102362,0.0003856897,0.0002106608,0.0002648159,0.0008857501],"category_scores_gemma":[0.0001170825,0.0001582901,0.0001323175,0.00009237795,0.0001972232,0.0001939402,0.0002616103,0.0004100738,0.0002578392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003644033,"about_ca_system_score_gemma":0.0001374352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004680971,"about_ca_topic_score_gemma":0.0005638374,"domain_scores_codex":[0.999913,0.00001401223,0.000003959256,0.00001233903,0.00002228545,0.00003438229],"domain_scores_gemma":[0.9999467,0.00001075486,0.00001259745,0.000005793008,0.000008655033,0.00001540465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000732046,0.000009051609,0.00005948944,0.00001104926,0.000002636611,0.00002311722,0.000007579943,0.00006256645,0.9989895,0.0002278713,0.00001587036,0.0005180912],"study_design_scores_gemma":[0.00001029668,0.00007954023,0.0004032818,0.000002433077,0.000005146051,0.00005511252,0.00001384577,0.0004242196,0.9981093,0.00006223733,0.0008325656,0.000002009431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942151,0.000614911,0.003329758,0.00006044353,0.0000216485,0.00001592773,0.00003262167,0.00004345152,0.001666133],"genre_scores_gemma":[0.996767,0.0003953401,0.0008173464,0.00006646874,0.000006289273,0.00000847765,0.00005639267,0.00001568762,0.001866978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008857501,"threshold_uncertainty_score":0.002963126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006306789721989279,"score_gpt":0.2672706784894249,"score_spread":0.2609638887674356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}