{"id":"W1992965842","doi":"10.1016/j.molcel.2011.03.006","title":"Dot1 and Histone H3K79 Methylation in Natural Telomeric and HM Silencing","year":2011,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Plant Gene Expression Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research","keywords":"URA3; Biology; Gene silencing; DNA methylation; Methylation; Epigenetics; Genetics; Position effect; Saccharomyces cerevisiae; Computational biology; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001157201,0.0001130251,0.0001193725,0.00008805312,0.000029582,0.000009471595,0.00006828257,0.00008557577,0.00001588918],"category_scores_gemma":[0.00002925295,0.0001094752,0.00003384904,0.000095927,0.0000408347,0.000004026116,0.00009343653,0.00007756072,0.000003165771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009453316,"about_ca_system_score_gemma":0.00001447707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008534645,"about_ca_topic_score_gemma":0.00002851544,"domain_scores_codex":[0.999279,0.00006420409,0.000134163,0.000298268,0.0000796672,0.0001447473],"domain_scores_gemma":[0.9996914,0.000005276088,0.00005320468,0.0001715032,0.00002044771,0.00005813412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002283213,0.00001843325,0.001243666,0.00001050555,0.00001145046,0.00002167631,0.0001427801,0.000007943554,0.9964575,0.000005010325,0.0001722885,0.001885915],"study_design_scores_gemma":[0.0003217188,0.00004387126,0.003043498,0.000007050463,0.00002085278,0.000009743014,0.00007370747,0.0003893909,0.994324,0.00004043961,0.001571424,0.0001543644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915496,0.003998195,0.00110099,0.00001895647,0.00003876938,0.00007275788,0.000002389625,0.000006441279,0.003211901],"genre_scores_gemma":[0.9966663,0.0002275197,0.002409254,0.0001516525,0.00001233592,0.000005810288,0.00003701713,0.00001216241,0.0004779887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005116659,"threshold_uncertainty_score":0.4464269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006704460728492904,"score_gpt":0.2199594533752453,"score_spread":0.2132549926467524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}