{"id":"W1992970267","doi":"10.1021/bc0300293","title":"Efficient Synthesis of Isotopically Pure Isotope-Coded Affinity Tagging Reagents","year":2003,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institute for Theoretical Astrophysics","keywords":"Chemistry; Synthon; Yield (engineering); Reagent; Linker; Inert; Deuterium; Combinatorial chemistry; Isotope; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003507235,0.0005641311,0.0004432584,0.0003333033,0.0002254086,0.0004267752,0.0004868477,0.0004227869,0.00131199],"category_scores_gemma":[0.0003767067,0.0003705812,0.0002390565,0.0004330623,0.0002471136,0.0003371231,0.0004535323,0.0008247127,0.001458094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004846167,"about_ca_system_score_gemma":0.0004410393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002957219,"about_ca_topic_score_gemma":0.0006291008,"domain_scores_codex":[0.9997589,0.00003005355,0.00002600774,0.00005897609,0.00007879651,0.00004736436],"domain_scores_gemma":[0.9997993,0.00003159098,0.00004328282,0.00003984621,0.00004457923,0.00004146035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003718973,0.000008853164,0.00002660217,0.0000472784,0.000003254785,0.00004865921,0.00001876466,0.0001555897,0.995796,0.0004672193,0.0001088061,0.003281892],"study_design_scores_gemma":[0.000009283729,0.00004486547,0.00008592382,0.000002396135,0.000007463984,0.000117347,0.000003844138,0.0003887449,0.9935556,0.00004544583,0.005732884,0.000006151251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7084666,0.003721228,0.2680827,0.0003790454,0.0003188222,0.0005361313,0.002278856,0.001555244,0.01466139],"genre_scores_gemma":[0.7858466,0.003648635,0.1936104,0.0002062027,0.00007491723,0.000466462,0.003093547,0.0003323705,0.01272091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00131199,"threshold_uncertainty_score":0.004389048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02250481143923747,"score_gpt":0.2837966479054789,"score_spread":0.2612918364662414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}