{"id":"W1992997975","doi":"10.1016/j.bpc.2006.10.006","title":"Mechanism of stabilization of Bacillus circulans xylanase upon the introduction of disulfide bonds","year":2006,"lang":"en","type":"article","venue":"Biophysical Chemistry","topic":"Biofuel production and bioconversion","field":"Engineering","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Chemistry; Bacillus circulans; Xylanase; Disulfide bond; Mechanism (biology); Stereochemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000559521,0.00008149499,0.000130008,0.00001363529,0.00001509535,0.000002437708,0.00007954384,0.00007064512,0.00006219877],"category_scores_gemma":[0.00001286577,0.00006314375,0.00005945089,0.0001655405,0.00007246662,0.00003418963,0.00001605723,0.00006867892,0.00000165044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002374495,"about_ca_system_score_gemma":0.000008358213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002572925,"about_ca_topic_score_gemma":4.535315e-7,"domain_scores_codex":[0.9994429,0.000008259384,0.0002123226,0.0001154103,0.0001440234,0.00007708953],"domain_scores_gemma":[0.9996179,0.000009588447,0.0000722177,0.0002203828,0.00006240966,0.00001754221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001151169,0.00006324473,0.0000215539,0.0005064786,0.00001019919,1.008119e-7,0.00002020296,0.0008395994,0.9974623,0.0005031521,0.000387237,0.0001743901],"study_design_scores_gemma":[0.0001332911,0.00001621849,0.0001996952,0.000008541058,0.00001896017,0.000001223685,0.00006014295,0.003716631,0.994726,0.0003758417,0.000679945,0.00006350718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978718,0.00005541515,0.001219005,0.0001532109,0.00009815759,0.00006510558,0.00002854966,0.00003850783,0.0004702948],"genre_scores_gemma":[0.9994402,0.0000135384,0.00005318853,0.000001614174,0.0003512272,0.000002121121,0.00006275198,0.000008609942,0.00006675388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002877032,"threshold_uncertainty_score":0.2574928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004870177440809351,"score_gpt":0.1760820520128613,"score_spread":0.171211874572052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}