{"id":"W1993013835","doi":"10.1016/j.vaccine.2010.09.080","title":"PCPP (poly[di(carboxylatophenoxy)-phosphazene]) microparticles co-encapsulating ovalbumin and CpG oligo-deoxynucleotides are potent enhancers of antigen specific Th1 immune responses in mice","year":2010,"lang":"en","type":"article","venue":"Vaccine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of Saskatchewan","funders":"Idaho National Laboratory; Canadian Institutes of Health Research; Saskatchewan Health Research Foundation; Bill and Melinda Gates Foundation","keywords":"Ovalbumin; CpG Oligodeoxynucleotide; Immune system; Antigen; Chemistry; CpG site; In vivo; Molecular biology; Immunology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000820139,0.0003968524,0.0007620833,0.00036179,0.000253003,0.00003785624,0.0003899307,0.0003306103,0.0005545053],"category_scores_gemma":[0.0002434512,0.0003627465,0.000150892,0.0003760468,0.0002066338,0.0001998459,0.0001359425,0.000632751,0.00008676093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000380065,"about_ca_system_score_gemma":0.00008316722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005781002,"about_ca_topic_score_gemma":0.00008539498,"domain_scores_codex":[0.9974117,0.000394373,0.0009558924,0.0005091266,0.00007595964,0.0006529753],"domain_scores_gemma":[0.9982904,0.000511266,0.0004603013,0.0005907551,0.0001085187,0.00003871708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003471207,0.0002051691,0.04540814,0.00003476343,0.0001373766,0.00001715206,0.001067281,0.000004224771,0.9409418,0.0001626864,0.0001396808,0.008410488],"study_design_scores_gemma":[0.002131248,0.0001706592,0.3655896,0.0001163815,0.00001458828,0.00007636016,0.0007139918,0.000006238708,0.626684,0.00005020784,0.00419775,0.0002489285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9380574,0.06040964,0.0000250552,0.0003351582,0.0005898938,0.0003625307,0.00004097422,0.00006624597,0.000113067],"genre_scores_gemma":[0.9953587,0.003508758,0.0003008592,0.00007619432,0.00004415738,0.00002455943,0.00002480693,0.00005525157,0.0006067135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3201815,"threshold_uncertainty_score":0.9998825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009876459922914119,"score_gpt":0.2403876278569494,"score_spread":0.2305111679340353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}