{"id":"W1993024628","doi":"10.1016/j.cellimm.2005.10.005","title":"Adenosine is a negative regulator of NF-κB and MAPK signaling in human intestinal epithelial cells","year":2005,"lang":"en","type":"article","venue":"Cellular Immunology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Adenosine; Biology; Signal transduction; Regulator; Adenosine receptor; Cell biology; Purinergic signalling; MAPK/ERK pathway; NF-κB; Phosphorylation; Internal medicine; Inflammation; Immune system; p38 mitogen-activated protein kinases; Endocrinology; Receptor; Immunology; Gene; Biochemistry; Medicine; Agonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002379773,0.000221608,0.0003110094,0.0001307995,0.0000643836,0.00001102848,0.0002426409,0.0002694925,0.00009123539],"category_scores_gemma":[0.00006223196,0.0002356567,0.0000789126,0.0001188019,0.0003620107,0.000006190748,0.0002012195,0.0002137491,0.00001347422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002780787,"about_ca_system_score_gemma":0.00006394171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006528686,"about_ca_topic_score_gemma":0.00002005917,"domain_scores_codex":[0.9985724,0.0001297693,0.0004286188,0.0004414928,0.00009499036,0.0003327225],"domain_scores_gemma":[0.9992778,0.00003427806,0.0001899695,0.0003673736,0.00008127665,0.00004931831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001188272,0.00009733921,0.0004331937,0.00002302217,0.00005856954,0.00001251861,0.0004132919,0.00005661387,0.9976326,0.0003101803,0.00009009238,0.0007537558],"study_design_scores_gemma":[0.001165508,0.0004771949,0.0003139299,0.0000475903,0.00002143327,0.0000289083,0.0001023702,0.00006846811,0.9946988,0.0004633943,0.00238641,0.0002259954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956498,0.002757925,0.0009637355,0.0001397229,0.00009232108,0.0001839963,0.00002355274,0.00001304797,0.0001759224],"genre_scores_gemma":[0.996737,0.00004885562,0.00243787,0.0001234941,0.0001730501,0.00001254942,0.00004572932,0.00003372745,0.0003877002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002933798,"threshold_uncertainty_score":0.9609803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008853873615017249,"score_gpt":0.2226606886557038,"score_spread":0.2138068150406865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}