{"id":"W1993084701","doi":"10.1111/j.1399-3089.2005.00221.x","title":"Co‐stimulation blockade targeting CD154 and CD28/B7 modulates the induced antibody response after a pig‐to‐baboon cardiac xenograft","year":2005,"lang":"en","type":"article","venue":"Xenotransplantation","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute; IC Design Education Center; Mayo Clinic; National Institute of Allergy and Infectious Diseases; Biogen","keywords":"Medicine; Baboon; Immunology; Blockade; Transplantation; Antibody; CD154; Anti-thymocyte globulin; Internal medicine; Biology; CD40; Receptor; Cytotoxic T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001859655,0.0003290767,0.0002774722,0.0001339495,0.0001038527,0.0002052437,0.0001492538,0.0002189286,0.001494923],"category_scores_gemma":[0.0001367171,0.00009759946,0.0001316573,0.0000581406,0.000186882,0.0001456148,0.0001482502,0.0007838506,0.0003081988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001241763,"about_ca_system_score_gemma":0.0001452916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001632248,"about_ca_topic_score_gemma":0.0002849566,"domain_scores_codex":[0.9998376,0.00003394979,0.00001059584,0.00002854576,0.0000230245,0.00006618797],"domain_scores_gemma":[0.9998066,0.00004039953,0.00003731197,0.00001316747,0.00001256169,0.00009000098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00085559,0.0003832262,0.001572258,0.00002447019,0.00000816947,0.0001080524,0.00001821471,0.00007657849,0.9950186,0.00002629119,0.00004373931,0.001864808],"study_design_scores_gemma":[0.0002506621,0.01999746,0.04012371,0.00002650542,0.00008102052,0.001402324,0.00009439011,0.00222851,0.9340039,0.00004691658,0.001734907,0.000009623026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992189,0.0002832293,0.0001888635,0.00001141344,0.00000888785,0.000007959415,0.00002086995,0.000007368019,0.0002524382],"genre_scores_gemma":[0.9987001,0.0003110426,0.0003326991,0.00002937251,0.00001860117,0.00002161309,0.0001176103,0.000003764833,0.0004652898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001494923,"threshold_uncertainty_score":0.005001009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01128979090525256,"score_gpt":0.3057851398439651,"score_spread":0.2944953489387125,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}