{"id":"W1993110082","doi":"10.1016/j.chembiol.2008.03.009","title":"Sweetly Expanding Enzymatic Glycodiversification","year":2008,"lang":"en","type":"letter","venue":"Chemistry & Biology","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Substrate specificity; Substrate (aquarium); Directed evolution; Enzyme; Catalysis; Biology; Nanotechnology; Enzyme catalysis; Biochemistry; Chemistry; Materials science; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008622739,0.0007646937,0.0008675724,0.0000491494,0.0002631173,0.000049442,0.001003187,0.003474922,0.009160973],"category_scores_gemma":[0.0002689041,0.0008057444,0.0004673715,0.0001554172,0.000482111,0.00005911182,0.0001956161,0.002188224,0.000308426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003802549,"about_ca_system_score_gemma":0.0001779813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002489363,"about_ca_topic_score_gemma":1.720737e-7,"domain_scores_codex":[0.9970188,0.00003156959,0.000684552,0.001178492,0.0002584198,0.0008282131],"domain_scores_gemma":[0.9974865,0.0003812829,0.0005579792,0.001319942,0.0001173221,0.0001369939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001331521,0.0000217422,0.00006083499,0.0009154517,0.0001100114,0.0002263358,0.00006102215,5.244523e-7,0.6159154,4.860526e-7,0.3824107,0.0002642424],"study_design_scores_gemma":[0.0001968549,0.000003132155,7.664128e-7,0.0001020736,0.00008285751,0.0001925574,0.00005046731,0.00001449996,0.5210454,0.00006626103,0.4777245,0.0005205812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.3596953,0.003721067,0.00006551647,0.1741012,0.001061107,0.0003178611,0.001943553,0.001532813,0.4575615],"genre_scores_gemma":[0.5003532,0.0040421,0.0005955041,0.1930765,0.05066988,0.0007631346,0.05319643,0.0007441377,0.1965591],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.2610024,"threshold_uncertainty_score":0.9994394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02878359794066052,"score_gpt":0.2389233353495196,"score_spread":0.2101397374088591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}