{"id":"W1993118284","doi":"10.1089/107999003321455462","title":"CD2-CD48 Interactions Promote Cytotoxic T Lymphocyte Induction and Function: Anti-CD2 and Anti-CD48 Antibodies Impair Cytokine Synthesis, Proliferation, Target Recognition/Adhesion, and Cytotoxicity","year":2003,"lang":"en","type":"article","venue":"Journal of Interferon & Cytokine Research","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Cytotoxic T cell; Perforin; CTL*; Granzyme B; Biology; Granzyme; Molecular biology; Monoclonal antibody; Fas ligand; Cell biology; CD8; Chemistry; Antibody; Immunology; Antigen; Apoptosis; In vitro; Programmed cell death; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001715032,0.0006489766,0.0003496502,0.0001804282,0.0001622211,0.000551662,0.0002068855,0.0004207757,0.002484247],"category_scores_gemma":[0.0002060622,0.0001894235,0.0002362167,0.0001294094,0.0001870934,0.0004666381,0.0004006774,0.0005648661,0.0007166963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003244,"about_ca_system_score_gemma":0.000159286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002038502,"about_ca_topic_score_gemma":0.0002407721,"domain_scores_codex":[0.9996636,0.00007077806,0.00002746014,0.00004452764,0.00005579805,0.0001379391],"domain_scores_gemma":[0.9997801,0.00006060329,0.00004944646,0.00002738877,0.00001953631,0.00006290313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002005126,0.0000390093,0.0002186458,0.00003099114,0.00000523862,0.00007208343,0.000006986275,0.00004842024,0.9985744,0.00005171206,0.00002946537,0.0007226184],"study_design_scores_gemma":[0.00004733472,0.0001931487,0.00235836,0.000005546641,0.00001617239,0.0003506066,0.00001304154,0.0007440766,0.9944904,0.00003747971,0.001741193,0.000002697697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960167,0.001670331,0.001063792,0.00005508268,0.00001716418,0.00001108012,0.00005596137,0.00004865259,0.001061096],"genre_scores_gemma":[0.9969634,0.0005731989,0.0008809995,0.00004981392,0.00002630013,0.00002898143,0.0001885812,0.00002034883,0.001268357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002484247,"threshold_uncertainty_score":0.008310556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0399140599266958,"score_gpt":0.2981273854771628,"score_spread":0.258213325550467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}