{"id":"W1993125271","doi":"10.1038/sj.cgt.7700807","title":"Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70","year":2005,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kinexus Bioinformatics Corporation (Canada)","funders":"Science Foundation Ireland","keywords":"Nitroreductase; Immune system; Heat shock protein; Bystander effect; Shock (circulatory); Chemistry; Virology; Cell biology; Hsp70; Biology; Prodrug; Medicine; Biochemistry; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003452835,0.0009323588,0.0004380786,0.00056701,0.0002636495,0.0004288953,0.0003722188,0.000494447,0.001924928],"category_scores_gemma":[0.0002083917,0.0002359438,0.0003937833,0.0002778773,0.0005182175,0.0003012926,0.0002554629,0.001630789,0.0004267641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006390428,"about_ca_system_score_gemma":0.0003932622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009665709,"about_ca_topic_score_gemma":0.0008632084,"domain_scores_codex":[0.9996325,0.00007560157,0.0000240842,0.00004832288,0.00006349912,0.0001560538],"domain_scores_gemma":[0.9997576,0.00008518039,0.00004711094,0.00004672631,0.000009876892,0.00005354521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005321434,0.0001964036,0.0001254835,0.00003096513,0.00001153585,0.00007716011,0.00001497293,0.0002393762,0.9972064,0.0002869234,0.00007861364,0.001200009],"study_design_scores_gemma":[0.0001244486,0.000904382,0.0009550401,0.000005258863,0.00002765061,0.0001606917,0.00001483273,0.001619257,0.9952763,0.00005461017,0.0008519468,0.000005541392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947788,0.0007360049,0.001593325,0.0001335851,0.0001270879,0.00007660977,0.000226126,0.0001811783,0.002147279],"genre_scores_gemma":[0.9974706,0.0002097277,0.0007813135,0.00003762402,0.00002258926,0.00003598493,0.0002099056,0.00001619143,0.001216015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001924928,"threshold_uncertainty_score":0.006439567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0287856837523703,"score_gpt":0.3252477268296544,"score_spread":0.2964620430772841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}