{"id":"W1993235805","doi":"10.1021/bi201335t","title":"Revisiting Peptide Amphiphilicity for Membrane Pore Formation","year":2011,"lang":"en","type":"article","venue":"Biochemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; PROTEO","funders":"","keywords":"Peptide; Chemistry; Vesicle; Amphiphile; Selectivity; Membrane; Calcein; Bilayer; Lipid bilayer; Biophysics; Micelle; Stereochemistry; Biochemistry; Organic chemistry; Aqueous solution; Copolymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000334038,0.0002237238,0.0001848443,0.0001294662,0.0001844093,0.0003344676,0.0001570277,0.0002681068,0.0007314602],"category_scores_gemma":[0.0004109208,0.0001069393,0.0001535744,0.0000822251,0.0002568117,0.0003580436,0.0002489079,0.0004211052,0.00023615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001684339,"about_ca_system_score_gemma":0.000185528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007880008,"about_ca_topic_score_gemma":0.0001205791,"domain_scores_codex":[0.9998732,0.00003644909,0.00001312249,0.00001794637,0.0000343744,0.00002497712],"domain_scores_gemma":[0.9997572,0.0001110039,0.00004599621,0.00001508517,0.00003739134,0.00003323806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004001447,0.00001422045,0.000138711,0.00005754928,0.000002383818,0.00007814857,0.00001806819,0.0001671284,0.9968131,0.0003455569,0.000009827106,0.002315226],"study_design_scores_gemma":[0.00002126175,0.0003524163,0.0009630622,0.00001390309,0.00001276812,0.0003806131,0.00001779329,0.001353295,0.9941076,0.0002253489,0.002544912,0.000006959078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925372,0.001662681,0.003997272,0.000114511,0.0000190696,0.00003926299,0.00003229057,0.00002523239,0.001572483],"genre_scores_gemma":[0.9948814,0.001002079,0.003585007,0.00006082856,0.00001506506,0.00002194926,0.00003735461,0.00001108188,0.0003852099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007314602,"threshold_uncertainty_score":0.002447009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02462187742307661,"score_gpt":0.2246970807725188,"score_spread":0.2000752033494422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}