{"id":"W1993240362","doi":"10.1016/j.bmcl.2009.02.076","title":"Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products","year":2009,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Chicoutimi","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Chemistry; Cytotoxicity; Stereochemistry; Chemical synthesis; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002761935,0.0003232668,0.0003929139,0.00003390469,0.00009775811,0.00002068958,0.0002104302,0.0001762795,0.00002973677],"category_scores_gemma":[0.0004554875,0.0002635777,0.00005163926,0.0001697693,0.0003016881,0.00001195262,0.0001160817,0.000205889,0.000001006492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003558273,"about_ca_system_score_gemma":0.00008685535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003827362,"about_ca_topic_score_gemma":0.00000315745,"domain_scores_codex":[0.998516,0.00005641123,0.0002489422,0.000622014,0.0002115563,0.0003451295],"domain_scores_gemma":[0.9990473,0.00005357652,0.0001765058,0.000489962,0.00008609063,0.0001464968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002802779,0.00006795891,0.0001642031,0.0001569204,0.00009001247,0.000009436456,0.00007266411,2.324635e-7,0.9946687,0.000003090255,0.001217908,0.003268544],"study_design_scores_gemma":[0.0002869246,0.0001881857,0.004551759,0.0000796672,0.00007254285,0.0001729756,0.0001045064,0.000007082059,0.9931921,0.00001144948,0.001051891,0.0002809016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868194,0.002255109,0.00001518389,0.01044998,0.00009349003,0.0002182627,0.00001579668,0.00002086907,0.0001119129],"genre_scores_gemma":[0.9975832,0.0009390959,0.0001002184,0.0007300659,0.0004739376,0.000003272487,0.00001968852,0.00002400205,0.0001265051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01076381,"threshold_uncertainty_score":0.9999816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01079973757100211,"score_gpt":0.2225622172563518,"score_spread":0.2117624796853497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}