{"id":"W1993266955","doi":"10.1124/jpet.106.106989","title":"WAY-163909 [(7 bR,10 aR)-1,2,3,4,8,9,10,10 a-Octahydro-7 bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole]: A Novel 5-Hydroxytryptamine 2C Receptor-Selective Agonist with Preclinical Antipsychotic-Like Activity","year":2006,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":145,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Pharmacology; Dizocilpine; Catalepsy; Phencyclidine; Stereotypy; Agonist; Prepulse inhibition; Dopamine; Microdialysis; NMDA receptor; Neurotransmission; Internal medicine; Endocrinology; Receptor; Amphetamine; Haloperidol; Psychology; Extracellular; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002205592,0.0006053348,0.0007942822,0.000355399,0.0002445667,0.0002902679,0.000716502,0.0005296965,0.004865891],"category_scores_gemma":[0.0002250148,0.0003250699,0.0002472939,0.0002703495,0.0003798481,0.0004786632,0.0001610923,0.0013551,0.001996493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003102125,"about_ca_system_score_gemma":0.0006829571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001269134,"about_ca_topic_score_gemma":0.004158917,"domain_scores_codex":[0.999864,0.00002823563,0.00001642698,0.00001695985,0.0000254203,0.00004900742],"domain_scores_gemma":[0.9998465,0.00002122175,0.00003065249,0.00001498249,0.00001217482,0.00007450868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005704321,0.001925451,0.0005586701,0.0003182895,0.0001149275,0.0003375089,0.0001008181,0.0004387999,0.9645125,0.001010082,0.001998244,0.02298033],"study_design_scores_gemma":[0.01369688,0.08571526,0.02778194,0.0001498165,0.0004242418,0.003445248,0.0003492968,0.004934664,0.8422446,0.001310877,0.01972709,0.0002201028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831327,0.001712147,0.002193886,0.0004625575,0.000139563,0.0003701666,0.001923669,0.0006748274,0.009390587],"genre_scores_gemma":[0.9835917,0.002679807,0.004217645,0.0003078959,0.00007275202,0.0001910552,0.001573064,0.00005427905,0.007311935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004865891,"threshold_uncertainty_score":0.01627803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05137115001969406,"score_gpt":0.3635560120179265,"score_spread":0.3121848619982325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}