{"id":"W1993319098","doi":"10.1016/j.celrep.2014.04.049","title":"The CD3 Conformational Change in the γδ T Cell Receptor Is Not Triggered by Antigens but Can Be Enforced to Enhance Tumor Killing","year":2014,"lang":"en","type":"article","venue":"Cell Reports","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Ministerio de Economía y Competitividad; Deutsche Forschungsgemeinschaft","keywords":"T-cell receptor; CD3; Cell biology; Antigen; T cell; Biology; Immunology; Immune system; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001041632,0.0001717223,0.0001175664,0.00008639084,0.00009578467,0.0002495262,0.0001174172,0.0001542576,0.0009665061],"category_scores_gemma":[0.00011776,0.0000726228,0.0001332776,0.0001319675,0.0001884667,0.0001191317,0.000159561,0.0006034749,0.000242847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002217974,"about_ca_system_score_gemma":0.0001477533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002659175,"about_ca_topic_score_gemma":0.0004703462,"domain_scores_codex":[0.9998834,0.0000219551,0.00000975526,0.00001828812,0.00002554698,0.00004103759],"domain_scores_gemma":[0.9999343,0.00001518407,0.00001641906,0.00001654641,0.000005613528,0.00001189215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004556361,0.00001192738,0.00006801199,0.00001077986,0.000001587031,0.00001678104,0.000004106461,0.00005083027,0.9992313,0.00009218728,0.00001873,0.0004480575],"study_design_scores_gemma":[0.000009358711,0.00009259349,0.0008193766,0.000002121283,0.000004779009,0.00008029248,0.000007490125,0.0002479521,0.9975852,0.00002809203,0.001121199,0.000001515475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965836,0.0005150865,0.001549153,0.00006707086,0.00003277347,0.00001174482,0.00008344429,0.00004041958,0.001116724],"genre_scores_gemma":[0.9984246,0.0002003148,0.0006634283,0.00004062635,0.000005346472,0.000008752344,0.00008102825,0.00000959212,0.0005663264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009665061,"threshold_uncertainty_score":0.003233314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307715117762362,"score_gpt":0.2429407037054419,"score_spread":0.2298635525278183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}