{"id":"W1993334838","doi":"10.1002/eji.200939646","title":"Critical role of lipid rafts in CD154‐mediated T cell signaling","year":2009,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; Hôpital Saint-Luc; Centre Hospitalier de l’Université de Montréal; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Lipid raft; CD154; Phosphorylation; Cell biology; Jurkat cells; Biology; Protein kinase C; p38 mitogen-activated protein kinases; Signal transduction; Kinase; T cell; CD40; Biochemistry; Protein kinase A; Immunology; Cytotoxic T cell; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001573519,0.000425902,0.0001689302,0.0002980349,0.0004453695,0.0004917141,0.0001425303,0.0004039726,0.001551441],"category_scores_gemma":[0.0001867332,0.0001583853,0.0001902807,0.0001185768,0.0003006625,0.00056211,0.0003636828,0.0003891948,0.0007197257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003866769,"about_ca_system_score_gemma":0.0003215769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002706884,"about_ca_topic_score_gemma":0.0003499346,"domain_scores_codex":[0.999878,0.00002574529,0.000007654542,0.00001910336,0.00003097309,0.00003842907],"domain_scores_gemma":[0.9999115,0.00002003755,0.00002347276,0.000005809701,0.00001645461,0.00002266424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003869138,0.00002818674,0.0002401303,0.0001088298,0.000006754721,0.0003474527,0.00003316968,0.0001408973,0.9953236,0.0005354541,0.00004881857,0.002799741],"study_design_scores_gemma":[0.00004581338,0.0002088032,0.002977521,0.00002437713,0.0000224818,0.0009010597,0.00009619913,0.001041604,0.9898722,0.001130684,0.003669143,0.00001000303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861556,0.00640395,0.003351285,0.0003996255,0.00004579248,0.00004328365,0.0001828957,0.00005835437,0.003359286],"genre_scores_gemma":[0.9947819,0.002494325,0.001289741,0.00003701711,0.00001800648,0.00002134624,0.0001053916,0.000007084034,0.001245098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001551441,"threshold_uncertainty_score":0.005190134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00714559165781687,"score_gpt":0.2159306856308101,"score_spread":0.2087850939729932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}