{"id":"W1993336170","doi":"10.1016/j.bioorg.2008.08.005","title":"Fluorescent isotope-coded affinity tag (FCAT) I: Design and synthesis","year":2008,"lang":"en","type":"article","venue":"Bioorganic Chemistry","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"European Commission; Canadian Institute for Theoretical Astrophysics","keywords":"Chemistry; Fluorophore; Fluorescence; Reagent; Cysteine; Isotope; Reactivity (psychology); Linker; Combinatorial chemistry; Biochemistry; Enzyme; Organic chemistry; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005114438,0.0007677151,0.0004251133,0.0003888753,0.0003851787,0.0008277127,0.001536199,0.0008251687,0.001485724],"category_scores_gemma":[0.0003258292,0.0003965487,0.0004138519,0.0005107813,0.0004432415,0.0006518427,0.0003527504,0.001104795,0.002154723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001519489,"about_ca_system_score_gemma":0.001103829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002404441,"about_ca_topic_score_gemma":0.002961259,"domain_scores_codex":[0.9996994,0.00002065657,0.00001929156,0.00008328411,0.00009917776,0.00007828431],"domain_scores_gemma":[0.9998473,0.00001426361,0.00002680878,0.00002050363,0.00005451124,0.0000366211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001474283,0.00005846242,0.0001142971,0.0001919763,0.00001378115,0.0000521437,0.00004054338,0.0007525402,0.9755933,0.003199995,0.0008191629,0.0190163],"study_design_scores_gemma":[0.00001091066,0.0000896721,0.00009628508,0.000003657311,0.0000122362,0.0000944522,0.000006767814,0.001247478,0.9859335,0.0001361852,0.01235864,0.00001016021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2238852,0.007510817,0.7489489,0.001006278,0.0005141437,0.00110779,0.002315611,0.002791886,0.01191935],"genre_scores_gemma":[0.5334367,0.008275125,0.4247178,0.0008877435,0.0001187408,0.0008587844,0.003885529,0.0004100844,0.02740956],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002404441,"threshold_uncertainty_score":0.01102471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02333285095765819,"score_gpt":0.2307123157429878,"score_spread":0.2073794647853296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}