{"id":"W1993373169","doi":"10.1186/1475-2859-9-70","title":"Production of functionalized polyhydroxyalkanoates by genetically modified Methylobacterium extorquens strains","year":2010,"lang":"en","type":"article","venue":"Microbial Cell Factories","topic":"biodegradable polymer synthesis and properties","field":"Materials Science","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Institute for Research in Immunology and Cancer; National Research Council Canada; BioPhage Pharma (Canada); Université de Montréal; Biotechnology Research Institute","funders":"Fundação Oswaldo Cruz; Université de Montréal; Natural Sciences and Engineering Research Council of Canada; Queen's University","keywords":"Polyhydroxyalkanoates; Metabolic engineering; Methanol; Zymomonas mobilis; Bacteria; Biochemistry; Synthetic biology; Chemistry; Protein engineering; Recombinant DNA; Methanol dehydrogenase; Substrate (aquarium); Organic chemistry; Biology; Fermentation; Gene; Enzyme; Ethanol fuel; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000315442,0.0008761812,0.0002971429,0.000285509,0.0001155004,0.000354339,0.0006450858,0.0004189548,0.0006512176],"category_scores_gemma":[0.0002919267,0.0001600918,0.0004255579,0.0003534964,0.0001838638,0.0002223669,0.0005967529,0.0007873718,0.0004705787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003755268,"about_ca_system_score_gemma":0.0002768507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001031062,"about_ca_topic_score_gemma":0.001108826,"domain_scores_codex":[0.9997424,0.00003187242,0.00003913833,0.00005053731,0.00009301185,0.00004305714],"domain_scores_gemma":[0.999739,0.00004742384,0.00008641347,0.00004798588,0.00004678408,0.00003233633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003748459,0.00003248138,0.0001124595,0.00002580387,0.00000499489,0.00003288338,0.000008776445,0.00008313957,0.9988878,0.00003046917,0.00001082168,0.0007328841],"study_design_scores_gemma":[0.000010546,0.0001754061,0.001104124,0.000005476546,0.0000152535,0.0001102833,0.00001628139,0.0005672479,0.9970216,0.00001828959,0.0009483547,0.000007142736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894893,0.0003599293,0.007675794,0.00008434606,0.00003999552,0.0001081557,0.0009448008,0.0001642093,0.00113355],"genre_scores_gemma":[0.9673257,0.0004175176,0.02475179,0.00005020516,0.0000140408,0.0001494895,0.003030035,0.0001065529,0.00415471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001031062,"threshold_uncertainty_score":0.002724648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01486250430095818,"score_gpt":0.2099139830991593,"score_spread":0.1950514787982011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}