{"id":"W1993373169","doi":"10.1186/1475-2859-9-70","title":"Production of functionalized polyhydroxyalkanoates by genetically modified Methylobacterium extorquens strains","year":2010,"lang":"en","type":"article","venue":"Microbial Cell Factories","topic":"biodegradable polymer synthesis and properties","field":"Materials Science","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Institute for Research in Immunology and Cancer; National Research Council Canada; BioPhage Pharma (Canada); Université de Montréal; Biotechnology Research Institute","funders":"Fundação Oswaldo Cruz; Université de Montréal; Natural Sciences and Engineering Research Council of Canada; Queen's University","keywords":"Polyhydroxyalkanoates; Metabolic engineering; Methanol; Zymomonas mobilis; Bacteria; Biochemistry; Synthetic biology; Chemistry; Protein engineering; Recombinant DNA; Methanol dehydrogenase; Substrate (aquarium); Organic chemistry; Biology; Fermentation; Gene; Enzyme; Ethanol fuel; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002166745,0.0002384505,0.0003124989,0.00005138308,0.0001933064,0.000106977,0.0002663545,0.0001737825,0.002884779],"category_scores_gemma":[0.00007280202,0.0001882319,0.00009547169,0.0001019181,0.0004150689,0.0001933259,0.00006321553,0.0001714268,0.00004786051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001764456,"about_ca_system_score_gemma":0.00009772407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005082921,"about_ca_topic_score_gemma":0.00009274318,"domain_scores_codex":[0.998557,0.00009614106,0.0003981414,0.0003935142,0.0002207676,0.000334434],"domain_scores_gemma":[0.9991995,0.00004400375,0.0001702714,0.0003470949,0.0001484561,0.00009067441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009281738,0.0001119863,0.0001163007,0.00005081851,0.00001151834,2.756984e-7,0.0003813129,0.000001063082,0.9956691,0.00008772399,0.002375715,0.001101347],"study_design_scores_gemma":[0.000174375,0.00006583313,0.0004260263,0.000007770558,0.00002881016,0.000003895901,0.00005990528,0.000002947088,0.9736421,0.00007203852,0.02529022,0.0002260407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992945,0.001904314,0.0002170376,0.0002937866,0.00336857,0.0001523692,0.0002687141,0.00008283091,0.0007674285],"genre_scores_gemma":[0.9945748,0.00004624251,0.001632426,0.00004493116,0.0002570917,0.00001259768,0.00004108184,0.00002630803,0.003364563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0229145,"threshold_uncertainty_score":0.9980267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01486250430095818,"score_gpt":0.2099139830991593,"score_spread":0.1950514787982011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}