{"id":"W1993418657","doi":"10.1016/j.molcel.2012.02.007","title":"The Sam68 STAR RNA-Binding Protein Regulates mTOR Alternative Splicing during Adipogenesis","year":2012,"lang":"en","type":"article","venue":"Molecular Cell","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill University; Université Laval; Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Biology; Adipogenesis; RNA-binding protein; RNA splicing; Alternative splicing; RNA; Cell biology; PI3K/AKT/mTOR pathway; Star (game theory); Computational biology; Genetics; Messenger RNA; Signal transduction; Gene; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004326621,0.0002191716,0.0001387123,0.00005420473,0.0004228485,0.00008297152,0.0003702711,0.000107581,0.0000154519],"category_scores_gemma":[0.00009543516,0.0001706989,0.0001417882,0.0001245196,0.00008312889,0.00001114552,0.0002591141,0.0001580224,0.00004687954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005135843,"about_ca_system_score_gemma":0.00004292943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006805704,"about_ca_topic_score_gemma":0.00001093044,"domain_scores_codex":[0.9981804,0.0001467411,0.000218986,0.0003341864,0.00030864,0.0008110543],"domain_scores_gemma":[0.9990617,0.0000179664,0.0001019813,0.0005163871,0.00007393972,0.00022801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007041619,0.0000338217,0.000627619,0.00002941962,0.00006751233,0.0000145122,0.00005493371,0.00004368959,0.9981157,0.00007014503,0.00007413255,0.000798053],"study_design_scores_gemma":[0.0003796875,0.00008351256,0.0005163991,0.00002434545,0.00001463347,0.000007421339,0.0001210457,0.00009309491,0.9944243,0.00001691961,0.004096187,0.0002224399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949307,0.002758188,0.0004642578,0.000107742,0.0001008719,0.000419213,0.000006895284,0.00001843049,0.001193665],"genre_scores_gemma":[0.9907755,0.0001137295,0.0006767621,0.00004845542,0.0002794154,0.00006933675,0.00002308885,0.00005607794,0.007957622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006763957,"threshold_uncertainty_score":0.6960897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008283015797166175,"score_gpt":0.2365480424271155,"score_spread":0.2282650266299493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}