{"id":"W1993475919","doi":"10.1006/dbio.2002.0628","title":"Dynamics of Dnmt1 Methyltransferase Expression and Intracellular Localization during Oogenesis and Preimplantation Development","year":2002,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":188,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal Victoria Hospital; McGill University; Montreal Children's Hospital","funders":"","keywords":"Biology; DNMT1; Methyltransferase; DNA methylation; Genomic imprinting; DNA methyltransferase; Embryo; Methylation; Oocyte; Blastocyst; Molecular biology; Embryogenesis; Cell biology; Genetics; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000154112,0.0001242677,0.000361614,0.0004158754,0.0003349581,0.0008006746,0.0003125011,0.0002687512,0.001600999],"category_scores_gemma":[0.0004757384,0.0002925313,0.0001579103,0.0003250024,0.0003116743,0.0006689805,0.0003495076,0.0007192029,0.0005292355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006967826,"about_ca_system_score_gemma":0.0002780002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001994153,"about_ca_topic_score_gemma":0.003813655,"domain_scores_codex":[0.9999061,0.000006640737,0.000004724678,0.00002648673,0.00002582322,0.00003016382],"domain_scores_gemma":[0.9996864,0.00008368063,0.00006608057,0.00002050909,0.00006683331,0.00007659891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005375144,0.00001433008,0.002697085,0.00004503631,0.000007995334,0.00005717101,0.0001282141,0.0001062691,0.9901176,0.000791554,0.0000967662,0.005400342],"study_design_scores_gemma":[0.00003419919,0.000162672,0.2092056,0.00002096238,0.00004083636,0.0002861754,0.0004283847,0.002379019,0.7809982,0.0006422131,0.005775527,0.00002616687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863577,0.003665179,0.004543885,0.0001185447,0.00002372221,0.000009762518,0.000543536,0.00008826798,0.004649303],"genre_scores_gemma":[0.991488,0.001172187,0.001392927,0.00004915612,0.00001963446,0.00003423093,0.0006706688,0.00005692229,0.005116257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001994153,"threshold_uncertainty_score":0.005355895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009727689739316885,"score_gpt":0.2178531796583265,"score_spread":0.2081254899190096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}