{"id":"W1993475919","doi":"10.1006/dbio.2002.0628","title":"Dynamics of Dnmt1 Methyltransferase Expression and Intracellular Localization during Oogenesis and Preimplantation Development","year":2002,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":188,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal Victoria Hospital; McGill University; Montreal Children's Hospital","funders":"","keywords":"Biology; DNMT1; Methyltransferase; DNA methylation; Genomic imprinting; DNA methyltransferase; Embryo; Methylation; Oocyte; Blastocyst; Molecular biology; Embryogenesis; Cell biology; Genetics; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001091282,0.0001204473,0.0001208022,0.00006498257,0.0000975884,0.000007616779,0.00004537012,0.00014454,0.00001899257],"category_scores_gemma":[0.00002296735,0.0001169549,0.0000137566,0.00005544247,0.00007294991,0.000005150564,0.00006584852,0.00003219952,0.000001304661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001934838,"about_ca_system_score_gemma":0.00001559706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006558511,"about_ca_topic_score_gemma":0.00003084537,"domain_scores_codex":[0.9992427,0.00005774847,0.0002521647,0.0002611066,0.00005433583,0.000131892],"domain_scores_gemma":[0.9997641,0.00001243956,0.00006689817,0.00006602256,0.00003778992,0.0000527769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002785748,0.00002449083,0.04063041,0.0000400483,0.00002192139,7.363129e-7,0.0002855041,0.00001600497,0.9444752,0.00003982977,0.000001892821,0.01443612],"study_design_scores_gemma":[0.0004244927,0.0000664379,0.01771841,0.00001396053,0.000007766825,0.00001216171,0.00009363572,0.0003654945,0.9805621,0.0000637608,0.0005236467,0.0001481324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779395,0.001921982,0.01982588,0.00002368135,0.00003941892,0.0001355208,0.00001297088,0.000006805851,0.00009422996],"genre_scores_gemma":[0.9891524,0.001751542,0.008616559,0.0000159452,0.00001621023,0.00001314749,0.0003721623,0.00001139394,0.00005058955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03608692,"threshold_uncertainty_score":0.4769281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009727689739316885,"score_gpt":0.2178531796583265,"score_spread":0.2081254899190096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}