{"id":"W1993507524","doi":"10.1128/iai.02495-14","title":"Sterilizing Immunity Elicited by Neisseria meningitidis Carriage Shows Broader Protection than Predicted by Serum Antibody Cross-Reactivity in <i>CEACAM1</i> -Humanized Mice","year":2014,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Neisseria meningitidis; Biology; Microbiology; Antibody; Immunity; Immune system; Virology; Antiserum; Strain (injury); Neisseriaceae; Humoral immunity; Immunology; Bacteria; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004114584,0.0009075995,0.0004993539,0.0006613302,0.0002423883,0.0005195047,0.0003496124,0.0009223919,0.001858161],"category_scores_gemma":[0.0002803588,0.0003934096,0.0005935953,0.000151183,0.0005441435,0.0004232657,0.0003257201,0.002583207,0.0005513232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004618402,"about_ca_system_score_gemma":0.0002281383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000800122,"about_ca_topic_score_gemma":0.0007907727,"domain_scores_codex":[0.9994591,0.00007824205,0.00005268095,0.0001599664,0.00008229545,0.000167726],"domain_scores_gemma":[0.999519,0.00007990486,0.0001121295,0.00008147742,0.00003274776,0.0001746933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004978153,0.0003300461,0.0003658837,0.00002658499,0.00001183268,0.00007611473,0.00003822974,0.00004899703,0.9978195,0.00008513412,0.00006379834,0.0006360637],"study_design_scores_gemma":[0.0002000927,0.00804814,0.01931255,0.00003132604,0.00006952213,0.001288503,0.00009732971,0.001656583,0.9667578,0.0001488891,0.002365253,0.00002402857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970892,0.000412157,0.0006936963,0.0001284051,0.00004157984,0.00004174385,0.0004241241,0.00009405866,0.001075106],"genre_scores_gemma":[0.9950358,0.0003706111,0.0008316775,0.0002414053,0.00003339573,0.00005856066,0.0007740873,0.00004165733,0.002612755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001858161,"threshold_uncertainty_score":0.006216228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246246906049283,"score_gpt":0.2694014648051376,"score_spread":0.2569389957446448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}