{"id":"W1993512309","doi":"10.1038/sj.mt.6300337","title":"Targeting the Untargetable: Oncolytic Virotherapy for the Cancer Stem Cell","year":2007,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jennerex Biotherapeutics (Canada)","funders":"","keywords":"Cancer stem cell; Stem cell; Cancer research; Oncolytic virus; Cancer; CD44; Cancer cell; Medicine; Leukemia; Virotherapy; Breast cancer; Immunology; Oncology; Biology; Internal medicine; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001546997,0.0007854024,0.0004819462,0.0001105347,0.0006289068,0.0002061984,0.002232986,0.001041365,0.0002042475],"category_scores_gemma":[0.00001519893,0.0004777654,0.0006391145,0.0003231333,0.0004080813,0.000005037168,0.000143642,0.001501536,0.00003058315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001275017,"about_ca_system_score_gemma":0.0005638195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001074477,"about_ca_topic_score_gemma":0.00005456969,"domain_scores_codex":[0.9957147,0.0005064172,0.000542073,0.00110297,0.0008228715,0.001310926],"domain_scores_gemma":[0.9971356,0.0002418555,0.000335532,0.001891202,0.0003046699,0.00009107819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001357284,0.00004593079,0.000009697347,0.00004298617,0.0006447767,0.00002712472,0.00007874805,0.0006189154,0.5203079,0.00000298537,0.4585635,0.01830015],"study_design_scores_gemma":[0.001013121,0.0009175783,0.000001905087,0.0000135851,0.0000400852,0.000003279171,0.00003053065,0.0001066913,0.4017521,0.00003335184,0.5956947,0.00039302],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03864796,0.3222018,0.03511121,0.5898225,0.00209675,0.01078962,0.0005546954,0.0001252726,0.0006501079],"genre_scores_gemma":[0.006539347,0.02440985,0.0002540917,0.9453128,0.00788883,0.002623241,0.0007143321,0.0006626688,0.01159484],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.3554903,"threshold_uncertainty_score":0.9997674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02381051672794346,"score_gpt":0.3084761163973184,"score_spread":0.2846655996693749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}