{"id":"W1993512309","doi":"10.1038/sj.mt.6300337","title":"Targeting the Untargetable: Oncolytic Virotherapy for the Cancer Stem Cell","year":2007,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jennerex Biotherapeutics (Canada)","funders":"","keywords":"Cancer stem cell; Stem cell; Cancer research; Oncolytic virus; Cancer; CD44; Cancer cell; Medicine; Leukemia; Virotherapy; Breast cancer; Immunology; Oncology; Biology; Internal medicine; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003137166,0.0004182328,0.0005577065,0.001076997,0.0002337002,0.001017924,0.0004495772,0.0006200227,0.007441896],"category_scores_gemma":[0.0003807071,0.0002470069,0.0005784268,0.0009461337,0.0002919303,0.001050499,0.0005346434,0.0007607486,0.001866476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006439096,"about_ca_system_score_gemma":0.001001665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008936602,"about_ca_topic_score_gemma":0.00194887,"domain_scores_codex":[0.9997504,0.00002843227,0.0000162019,0.00002928938,0.0001483171,0.00002740214],"domain_scores_gemma":[0.9999158,0.00001949757,0.00001636051,0.0000124185,0.00001991478,0.00001597768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005690798,0.0001542995,0.0004155119,0.003533624,0.0001108528,0.0006305505,0.0001446805,0.0007601749,0.6607581,0.007920043,0.03151775,0.2934854],"study_design_scores_gemma":[0.000140766,0.0004657453,0.001787964,0.000438959,0.0002247378,0.001823539,0.00005300073,0.002012363,0.510797,0.003554292,0.4786448,0.00005671747],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.1860242,0.5544056,0.1554829,0.01896842,0.009195983,0.001067833,0.006888284,0.003323755,0.06464306],"genre_scores_gemma":[0.4760185,0.3416384,0.07819868,0.004720957,0.001346661,0.0005247704,0.00652312,0.0007740359,0.0902549],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.007441896,"threshold_uncertainty_score":0.02489567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02381051672794346,"score_gpt":0.3084761163973184,"score_spread":0.2846655996693749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}