{"id":"W1993541117","doi":"10.1016/j.biomaterials.2008.12.040","title":"The effect of a hydroxamic acid-containing polymer on active matrix metalloproteinases","year":2009,"lang":"en","type":"article","venue":"Biomaterials","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Viron Therapeutics (Canada)","funders":"","keywords":"Hydroxamic acid; Matrix metalloproteinase; Methacrylic acid; Methacrylate; Polymer; Polymerization; Materials science; Chemistry; Polymer chemistry; Biochemistry; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003039521,0.0001587999,0.0001985591,0.00002793014,0.00009991288,0.00002872451,0.0001663403,0.000109401,0.00001497332],"category_scores_gemma":[0.00008607928,0.00009782028,0.0001054933,0.00004237339,0.00004078005,0.000003895977,0.00004030318,0.000009626222,0.0000134964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008533832,"about_ca_system_score_gemma":0.00002021188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001468762,"about_ca_topic_score_gemma":9.72185e-7,"domain_scores_codex":[0.9991,0.0001726734,0.0002012257,0.0002110723,0.0001121315,0.0002028441],"domain_scores_gemma":[0.9994816,0.00001872667,0.0001389276,0.0003023151,0.00001951062,0.00003891174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00117763,0.00001583434,0.000003180677,0.000007542049,0.00004904321,0.000003047259,0.000007983047,2.084938e-7,0.9953808,0.0002285996,0.00006848008,0.003057696],"study_design_scores_gemma":[0.0004821725,0.004196732,0.00004951607,0.00002762859,0.00002495377,0.000007655142,0.0000103706,9.724898e-7,0.9943557,0.0001096325,0.0006206084,0.0001140982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978615,0.001080338,0.00002495108,0.00007031876,0.0002097503,0.0003879438,0.0000296636,0.0000162245,0.0003192874],"genre_scores_gemma":[0.999442,0.00002913834,0.00003312856,0.00006733349,0.0002161503,0.0000469646,0.00003174528,0.00001248613,0.0001210125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004180897,"threshold_uncertainty_score":0.3988995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005007147919754207,"score_gpt":0.2562271505288659,"score_spread":0.2512200026091117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}