{"id":"W1993607907","doi":"10.1002/pmic.201100308","title":"Quantification of protein isoforms in mesenchymal stem cells by reductive dimethylation of lysines in intact proteins","year":2011,"lang":"en","type":"article","venue":"PROTEOMICS","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Gene isoform; Proteome; Lysine; Proteomics; Chemistry; Blot; Biochemistry; Protein isoform; Biology; Mesenchymal stem cell; Cell biology; Gene; Amino acid; Alternative splicing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004308007,0.0004391667,0.0002460995,0.0003854429,0.0002505618,0.0003252826,0.0002529788,0.0002390089,0.0004237983],"category_scores_gemma":[0.0003630249,0.0001776298,0.0002344459,0.0002793739,0.000361317,0.0002718393,0.0002590076,0.0003809929,0.0002087664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002812671,"about_ca_system_score_gemma":0.0002485941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005534545,"about_ca_topic_score_gemma":0.001153758,"domain_scores_codex":[0.9997258,0.00003216238,0.00002370233,0.00008350248,0.0001098742,0.00002498306],"domain_scores_gemma":[0.999706,0.0000591856,0.0001052501,0.00003386536,0.00006144412,0.00003421701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004188535,0.000003432723,0.0002821248,0.00002086694,0.000004895083,0.000008762874,0.00001282941,0.00002139796,0.9988225,0.00002230651,0.000005178485,0.000753721],"study_design_scores_gemma":[0.000003599597,0.00007560378,0.005020796,0.000002204393,0.00001501355,0.0001118419,0.00001852265,0.0004776616,0.9936463,0.00004159618,0.0005832173,0.000003749931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9753277,0.001114852,0.02187807,0.00006556512,0.00001580152,0.00004467624,0.0008665411,0.00008025167,0.0006066223],"genre_scores_gemma":[0.9469309,0.001982434,0.04703066,0.00009856893,0.0000157901,0.0001194269,0.001990289,0.00005388743,0.001778178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005534545,"threshold_uncertainty_score":0.002278328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02231156157926758,"score_gpt":0.2422286149514212,"score_spread":0.2199170533721536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}