{"id":"W1993607907","doi":"10.1002/pmic.201100308","title":"Quantification of protein isoforms in mesenchymal stem cells by reductive dimethylation of lysines in intact proteins","year":2011,"lang":"en","type":"article","venue":"PROTEOMICS","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Gene isoform; Proteome; Lysine; Proteomics; Chemistry; Blot; Biochemistry; Protein isoform; Biology; Mesenchymal stem cell; Cell biology; Gene; Amino acid; Alternative splicing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004382295,0.0001139842,0.0001788278,0.0001200984,0.00001321046,0.000004029233,0.0001206945,0.000163133,0.000004570193],"category_scores_gemma":[0.00002542336,0.0001096524,0.00004357105,0.000212027,0.00006290622,0.00001212016,0.00004196483,0.00008019161,8.250628e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002236256,"about_ca_system_score_gemma":0.00006552848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003163473,"about_ca_topic_score_gemma":0.00005666547,"domain_scores_codex":[0.9989455,0.00008980644,0.0004706969,0.0002478912,0.0001093456,0.0001367371],"domain_scores_gemma":[0.9992963,0.000005535002,0.0003281872,0.0002328406,0.0001130047,0.00002410234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000149668,0.0001934458,0.01092247,0.0000633037,0.00000926333,1.402477e-7,0.0003953137,0.0001094159,0.9846884,0.0001039688,0.000001060802,0.003363536],"study_design_scores_gemma":[0.0003529313,0.0002631073,0.00759958,0.00003982216,0.000003899877,1.307358e-7,0.0001160506,0.0002049203,0.9906529,0.0006193821,0.0000336015,0.0001137175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879242,0.000314413,0.0101724,0.00001427588,0.00002852995,0.001308869,0.00001929454,0.000003018155,0.0002149884],"genre_scores_gemma":[0.9909888,0.00009197213,0.008696726,0.0000014895,0.00001649656,0.00009132185,0.00004459975,0.00001509341,0.00005348122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005964446,"threshold_uncertainty_score":0.4471494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02231156157926758,"score_gpt":0.2422286149514212,"score_spread":0.2199170533721536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}