{"id":"W1993612411","doi":"10.1038/gt.2011.91","title":"Efficient cochlear gene transfection in guinea-pigs with adeno-associated viral vectors by partial digestion of round window membrane","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"National Eye Institute","keywords":"Round window; Transfection; Cochlea; Biology; Genetic enhancement; Adeno-associated virus; Collagenase; Viral vector; Gene delivery; Inner ear; Cell biology; Vector (molecular biology); Molecular biology; Gene; Recombinant DNA; Anatomy; Genetics; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007790553,0.000840764,0.0004597258,0.0006409947,0.0003101563,0.0004733985,0.0006151224,0.0008363744,0.002019992],"category_scores_gemma":[0.0003871272,0.0005533785,0.0006780322,0.0002088347,0.0006788714,0.0005885793,0.0004714543,0.001057328,0.001122247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002428535,"about_ca_system_score_gemma":0.0004656705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006653874,"about_ca_topic_score_gemma":0.0009399314,"domain_scores_codex":[0.9996401,0.0000499249,0.00003676705,0.00009544763,0.00006877675,0.0001089544],"domain_scores_gemma":[0.9996707,0.0001127488,0.00008009721,0.00006946315,0.0000272018,0.00003977871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005959499,0.0000129742,0.00002532695,0.00002834001,0.000003695017,0.00004172436,0.00002630677,0.00003206567,0.9984778,0.0003738857,0.00002061733,0.0008976551],"study_design_scores_gemma":[0.00002041182,0.0002116717,0.0003813423,0.00001137148,0.00001971029,0.0001736407,0.0000154945,0.000378742,0.9967678,0.00008203042,0.001932606,0.000005198106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8727159,0.003536594,0.1134953,0.000416696,0.0003888874,0.000816369,0.001158827,0.001117617,0.006353734],"genre_scores_gemma":[0.9198861,0.003835519,0.05918409,0.0001075999,0.0000664179,0.0006879841,0.001465849,0.0002153513,0.014551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002019992,"threshold_uncertainty_score":0.006757557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03537903974621633,"score_gpt":0.2426613134535286,"score_spread":0.2072822737073123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}