{"id":"W1993645861","doi":"10.3109/09687688.2012.748939","title":"Use of molecular modelling to probe the mechanism of the nucleoside transporter NupG","year":2012,"lang":"en","type":"article","venue":"Molecular Membrane Biology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Fondation pour la Recherche Médicale; University of Leeds; Wellcome Trust","keywords":"Symporter; Major facilitator superfamily; Lactose permease; Nucleoside; Transporter; Nucleotide; Cysteine; Chemistry; Biochemistry; Biology; Computational biology; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002724866,0.0002135729,0.000257327,0.00004585094,0.00005959783,0.000006195176,0.0004408812,0.0002151241,0.00002215867],"category_scores_gemma":[0.00004844261,0.000134203,0.0002546499,0.000176381,0.0001336242,0.000005954749,0.0001475343,0.000124883,0.000003274556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006112182,"about_ca_system_score_gemma":0.00004541294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001020651,"about_ca_topic_score_gemma":0.000002257173,"domain_scores_codex":[0.998621,0.000196443,0.0003785582,0.0002789665,0.0001448253,0.0003802066],"domain_scores_gemma":[0.9989392,0.00002423023,0.0001616257,0.0006838788,0.0001033928,0.00008770842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006121309,0.00006231096,0.0004623611,0.00002426115,0.000105473,0.000001763185,0.0001498217,0.005065493,0.9796758,0.01422473,0.00007468937,0.00009212003],"study_design_scores_gemma":[0.0002118734,0.0001590816,0.0001232999,0.00002172365,0.00007998904,0.00001768472,0.00003026948,0.0001514997,0.9937274,0.0004082528,0.004901477,0.0001674881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8557781,0.001250949,0.1419295,0.0003016588,0.0001570754,0.0003719941,0.00002245554,0.000006974159,0.0001813293],"genre_scores_gemma":[0.9951134,0.0000402599,0.003447632,0.001154169,0.00008393636,0.0000287197,0.00003002734,0.00003701333,0.00006486876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1393353,"threshold_uncertainty_score":0.5472642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02219788366584117,"score_gpt":0.2333473781309342,"score_spread":0.211149494465093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}