{"id":"W1993669313","doi":"10.1038/sj.cgt.7700757","title":"Intratumoral administration of immature dendritic cells following the adenovirus vector encoding CD40 ligand elicits significant regression of established myeloma","year":2004,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"CD40; CD8; Immune system; Biology; Transgene; Immunotherapy; Genetic enhancement; Cancer research; In vivo; CD154; Apoptosis; Immunology; Dendritic cell; Cytotoxic T cell; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001885079,0.0004648677,0.0004767641,0.0003999784,0.0002078361,0.0003905219,0.0001628702,0.0003367054,0.001035881],"category_scores_gemma":[0.0001296417,0.0001589164,0.0002494617,0.0002785595,0.0003443478,0.0002268629,0.0001483555,0.001200434,0.0003327667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000514739,"about_ca_system_score_gemma":0.0005073171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001200098,"about_ca_topic_score_gemma":0.001495032,"domain_scores_codex":[0.9998156,0.0000155881,0.000009562271,0.00002532741,0.00005027767,0.00008363281],"domain_scores_gemma":[0.9998102,0.00005146011,0.00003478547,0.00003623863,0.00001503858,0.00005237273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005049879,0.0003154856,0.0001844245,0.00003054586,0.000008760564,0.00007377828,0.00002630919,0.0001684507,0.9950894,0.0002353982,0.0001610495,0.003201439],"study_design_scores_gemma":[0.00008678224,0.001255997,0.001294413,0.00000326554,0.00002333023,0.0001460926,0.00001578034,0.0007926387,0.9947017,0.00006065019,0.001615497,0.000003787294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945147,0.00111044,0.001573977,0.0001500439,0.0001018531,0.00003948119,0.0002175167,0.0001711116,0.002120993],"genre_scores_gemma":[0.9947084,0.0006268471,0.0006991595,0.00003693519,0.00003412595,0.00002050877,0.0003009278,0.00002363094,0.003549383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001200098,"threshold_uncertainty_score":0.003734767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01638334936687498,"score_gpt":0.2689878248838266,"score_spread":0.2526044755169516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}