{"id":"W1993669313","doi":"10.1038/sj.cgt.7700757","title":"Intratumoral administration of immature dendritic cells following the adenovirus vector encoding CD40 ligand elicits significant regression of established myeloma","year":2004,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"CD40; CD8; Immune system; Biology; Transgene; Immunotherapy; Genetic enhancement; Cancer research; In vivo; CD154; Apoptosis; Immunology; Dendritic cell; Cytotoxic T cell; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003034312,0.0002532343,0.0004396258,0.00009895635,0.0002144649,0.0000231678,0.0003724605,0.0002361444,0.0001209554],"category_scores_gemma":[0.00003088847,0.0001641791,0.0002134996,0.0002828268,0.0002377211,0.0001412457,0.00002556088,0.0002972511,0.000007255655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007006551,"about_ca_system_score_gemma":0.0004343635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001643127,"about_ca_topic_score_gemma":0.00001605897,"domain_scores_codex":[0.9985975,0.0002371621,0.0004949087,0.0002540232,0.00008907977,0.0003273411],"domain_scores_gemma":[0.9989923,0.0001559948,0.0003349223,0.0003972241,0.0001020024,0.00001751155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004091952,0.0001168786,0.0000835202,0.00002237201,0.0002752822,0.000007909579,0.002126338,0.00004245451,0.9874586,0.00009945779,0.0001033504,0.005571884],"study_design_scores_gemma":[0.002368714,0.0006314196,0.004119853,0.0002595184,0.00004114936,0.00002382362,0.0004421984,7.136868e-7,0.9905894,0.00008846466,0.001252476,0.0001822593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9338373,0.06399368,0.00008187604,0.0003098367,0.001295862,0.0003697925,0.00003834466,0.00002871857,0.00004457482],"genre_scores_gemma":[0.9941106,0.00524679,0.00006507376,0.0001452971,0.00006724024,0.00004721275,0.00002696532,0.00003016027,0.0002606756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06027327,"threshold_uncertainty_score":0.669503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01638334936687498,"score_gpt":0.2689878248838266,"score_spread":0.2526044755169516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}