{"id":"W1993673819","doi":"10.1371/journal.pone.0013823","title":"Regulation and Cytoprotective Role of Hexokinase III","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Northwestern University; American Heart Association","keywords":"Mitochondrion; Cell biology; Biology; Programmed cell death; Transcription factor; Post-translational regulation; Mitochondrial biogenesis; Oxidative phosphorylation; Biochemistry; Reactive oxygen species; Apoptosis; Gene; Phosphorylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008260225,0.0002290182,0.0001213827,0.00006519581,0.00008180778,0.0002692396,0.0001269431,0.0001162764,0.000898788],"category_scores_gemma":[0.00007855354,0.000053089,0.0001671271,0.00008567356,0.0002193785,0.0001304428,0.0001177009,0.0002990519,0.000219354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003943921,"about_ca_system_score_gemma":0.0001828913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005854523,"about_ca_topic_score_gemma":0.0002967694,"domain_scores_codex":[0.9999433,0.000007155562,0.000006395032,0.00001634057,0.00001173761,0.00001506951],"domain_scores_gemma":[0.9998811,0.00001309209,0.0000468293,0.00001019446,0.00002359295,0.00002504716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003229093,0.00001749124,0.001152339,0.00005952352,0.000006226032,0.00003799785,0.00001001009,0.00005057895,0.9969381,0.0001007491,0.00004640606,0.001257736],"study_design_scores_gemma":[0.00002065334,0.0002126769,0.02374477,0.00001067331,0.0000222674,0.0002578188,0.00003658762,0.0007002943,0.9732593,0.0001120066,0.00161918,0.000003666829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906415,0.003288842,0.00399946,0.000192076,0.00005546469,0.00002116608,0.0005090944,0.00005065089,0.001241612],"genre_scores_gemma":[0.9963036,0.0009319169,0.001111059,0.0000604035,0.00001161391,0.00001521706,0.0004751745,0.00001147324,0.001079519],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000898788,"threshold_uncertainty_score":0.003006697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009062775383745478,"score_gpt":0.2031774118569518,"score_spread":0.1941146364732063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}