{"id":"W1993713215","doi":"10.1080/14660820310011278","title":"Relevance of oxidative injury in the pathogenesis of motor neuron diseases","year":2003,"lang":"en","type":"review","venue":"Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Oxidative stress; SOD1; Reactive oxygen species; Superoxide dismutase; Oxidative phosphorylation; DNA damage; Pathogenesis; Biology; Reactive nitrogen species; Cell biology; Chemistry; Biochemistry; Immunology; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004265886,0.0006036412,0.0009813294,0.001198391,0.0002534474,0.0008939919,0.0006459505,0.0007788891,0.001486423],"category_scores_gemma":[0.0003107361,0.0001622682,0.0004495849,0.001209907,0.0003660225,0.0008243969,0.0004694793,0.0009002627,0.0006991856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005930419,"about_ca_system_score_gemma":0.0008257984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006519675,"about_ca_topic_score_gemma":0.0007794269,"domain_scores_codex":[0.9997668,0.00004185236,0.00004498169,0.00004600345,0.0000706174,0.00002976564],"domain_scores_gemma":[0.999828,0.00004650305,0.00004125784,0.000004289308,0.000062359,0.00001757133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000475409,0.0001486694,0.002501712,0.04977347,0.0004063175,0.003104691,0.000755934,0.001288276,0.04103646,0.007600605,0.02082527,0.8720831],"study_design_scores_gemma":[0.0000413624,0.000820191,0.01341319,0.007190272,0.0004986763,0.009586755,0.0005707108,0.0003642244,0.008019512,0.008348393,0.9510809,0.00006574349],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001114001,0.9973,0.0002405124,0.0003196266,0.0002150132,0.000007774259,0.00001999384,0.000009144525,0.0007740403],"genre_scores_gemma":[0.004292891,0.9944748,0.0002401174,0.0001717068,0.0002596768,0.000008196048,0.00003249824,0.000001569398,0.0005184718],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001486423,"threshold_uncertainty_score":0.004972577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04374631133964774,"score_gpt":0.3062860427629415,"score_spread":0.2625397314232937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}